Histone H2A (hydroxyl Y39) Antibody (YA381)
Histone H2A (hydroxyl Y39) Antibody (YA381) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2A (hydroxyl Y39).
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P
-
Reactivity :
Human, Mouse
-
Formulation:
Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|---|
| Dilution Ratio | 1:500 | 1:50 |
Product Details
Histone H2A (hydroxyl Y39) Antibody (YA381) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Histone H2A (hydroxyl Y39).
-
Host Rabbit
-
Clonality Recombinant, Monoclonal
-
Species ReactivityHuman, Mouse
-
Observed Molecular WeightObserved band size: 15 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 14 kDa
Entrez Gene: 3012 Human ; 317772 Human ; 8335 Human ; 8338 Human ; 319166 Mouse ;
SwissProt: P04908 Human ; P0C0S8 Human ; P20671 Human ; Q16777 Human ; Q6FI13 Human ; Q7L7L0 Human ; Q8IUE6 Human ; Q93077 Human ; Q96KK5 Human ; Q96QV6 Human ; Q99878 Human ; P10812 Mouse ; P22752 Mouse ;
OMIM: 602786 Human
Synthetic peptide corresponding to Human Histone H2A.AA range:1-83.
Endogenous
Protein A affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Histone H2A core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
-
Subcellular Localization
Nucleus; Chromosome
-
Subunit
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA
-
SwissProt ID
-
Research Field
Epigenetics and Nuclear Signaling
Documentation
Powered by Bioz
