Acetyl-Histone H2A (Lys9) Antibody (YA9911)
(Synonyms: H2AK9ac; H2A; H2A1B; H2AFM; HIST1H2A; Histone H2A.2; Histone H2A/a)Based on 1 Customer Validation
Acetyl-Histone H2A (Lys9) Antibody (YA9911) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Acetyl-Histone H2A (Lys9).
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, ChIP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ChIP
ChIP: Chromatin Immunoprecipitation
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|---|---|---|---|---|
| Dilution Ratio | 1:1000 | 1:50 | 1:4000 | Recomend 0.5~2 μg for 25 μg of chromatin |
Product Details
Acetyl-Histone H2A (Lys9) Antibody (YA9911) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Acetyl-Histone H2A (Lys9).
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Host Rabbit
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 14 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 14 kDa
Synthetic peptide within Human Histone H2A aa 1-50 (acetyl K9).
Endogenous
affinity purified
Non-conjugated
Acetylated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.05% Sodium Azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Acetyl-Histone H2A is a Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
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Subcellular Localization
Nucleus; Chromosome
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Isoforms & Post-Translational Modification
Acetyl-Histone H2A has an amino acid length of 130, molecular weight is 14135 Da.
Deiminated on Arg-4 in granulocytes upon calcium entry. -
Subunit
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
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SwissProt ID
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Synonyms
H2AK9ac; H2A; H2A1B; H2AFM; HIST1H2A; Histone H2A.2; Histone H2A/a
Documentation