122 Results for "

hormone secretion

" in MedChemExpress (MCE) Product Catalog:
Products (122)

122 Results for "hormone secretion" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-50919
CAS No.: 131918-61-1
Target:  

VD/VDR

Research Areas:  

Metabolic Disease Cancer

Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure.
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11
11 Cited Publications
Cat. No.: HY-14734
CAS No.: 249921-19-5
Purity:  99.94%
Synonyms: RC-1291; ONO-7643
Target:  

GHSR

Research Areas:  

Endocrinology Cancer

Anamorelin (RC-1291) is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin can be used in the research of anorexia and cancer cachexia .
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11
11 Cited Publications
Cat. No.: HY-14734A
CAS No.: 861998-00-7
Purity:  99.59%
Synonyms: RC-1291 hydrochloride; ONO-7643 hydrochloride
Target:  

GHSR

Research Areas:  

Endocrinology Cancer

Anamorelin (RC-1291) hydrochloride is an orally active Ghrelin receptor agonist with an EC50 of 0.74 nM. Anamorelin hydrochloride can promote appetite, increase body weight, and stimulate the secretion of growth hormone and insulin-like growth factor-1. Anamorelin hydrochloride can be used in the research of anorexia and cancer cachexia .
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10
10 Cited Publications
Cat. No.: HY-P0055
CAS No.: 106612-94-6
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

GLP-1(7-37) is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.
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10
10 Cited Publications
Cat. No.: HY-P0054A
CAS No.: 107444-51-9
Synonyms: Glucagon-like peptide-1 (GLP-1)(7-36), amide; Human GLP-1 (7-36), amide
Target:  

GCGR

Research Areas:  

Metabolic Disease

GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretion.
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10
10 Cited Publications
Cat. No.: HY-P0054
CAS No.: 1119517-19-9
Synonyms: Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate
Target:  

GCGR

Research Areas:  

Metabolic Disease

GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.
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10
10 Cited Publications
Cat. No.: HY-P0055A
CAS No.: 1450806-98-0
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion .
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10
10 Cited Publications
Cat. No.: HY-P0054B
Synonyms: Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA
Target:  

GCGR

Research Areas:  

Metabolic Disease

GLP-1(7-36), amide TFA is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells .
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7
7 Cited Publications
Cat. No.: HY-103377
CAS No.: 220953-69-5
Purity:  99.87%
Target:  

CRFR

Antalarmin (hydrochloride) is an oral active non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory effects in arthritis models, and suppresses stress-induced gastric ulceration related to irritable bowel syndrome .
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5
5 Cited Publications
Cat. No.: HY-77839
CAS No.: 152-58-9
Synonyms: 11-Deoxycortisol; cortexolone; Reichstein's substance S
Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation .
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4
4 Cited Publications
Cat. No.: HY-P0093
CAS No.: 25126-32-3
Synonyms: Cholecystokinin octapeptide; CCK-8; SQ19844
Research Areas:  

Infection Cancer

Sincalide (Cholecystokinin octapeptide, CCK-8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK. Sincalide can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK .
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4
4 Cited Publications
Cat. No.: HY-P0093A
CAS No.: 70706-98-8
Synonyms: Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium
Research Areas:  

Infection Cancer

Sincalide ammonium (Cholecystokinin octapeptide ammonium, CCK-8 ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK‐8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide ammonium can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK .
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3
3 Cited Publications
Cat. No.: HY-P10138
CAS No.: 1884226-05-4
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Human GIP(3-30), amide is a high affinity antagonist of the human GIP receptor in vitro. Human GIP(3-30), amide has potential anti-obesity and anti-diabetic effects .
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3
3 Cited Publications
Cat. No.: HY-17613
CAS No.: 870964-67-3
Synonyms: KHK7580
Target:  

CaSR

Research Areas:  

Metabolic Disease

Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
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3
3 Cited Publications
Cat. No.: HY-P1235A
CAS No.: 1366000-58-9
Synonyms: Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate
Target:  

Endothelin Receptor

Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine acetate) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide acetate inhibits endothelin-1 secretion in a dose-dependent way.
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3
3 Cited Publications
Cat. No.: HY-P10138A
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Human GIP(3-30), amide TFA is the TFA salt form of human GIP(3-30), amide (HY-P10138). Human GIP(3-30), amide TFA is a high affinity antagonist of the human GIP receptor in vitro. Human GIP(3-30), amide TFA has potential anti-obesity and anti-diabetic effects .
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2
2 Cited Publications
Cat. No.: HY-P0276
CAS No.: 100040-31-1
Synonyms: Gastric Inhibitory Peptide (GIP), human
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

GIP, human, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human acts as an incretin hormone released from intestinal K cells in response to nutrient ingestion .
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2
2 Cited Publications
Cat. No.: HY-B1201
CAS No.: 51-24-1
Synonyms: 3,3',5-Triiodothyroacetic acid
Tiratricol is an orally available thyroid hormone analog that inhibits pituitary thyroid-stimulating hormone secretion. Tiratricol is an intracellular toxin neutralizer that inhibits LPS and lipid A cytotoxicity with IC50s of 20 μM and 32 μM, respectively. Tiratricol reduces TNF production in lipopolysaccharide-stimulated macrophages. Tiratricol also has antiviral activity and is an inhibitor of yellow fever virus (Flavivirus). It can bind to the RdRp domain of the viral NS5 protein to hinder YFV replication. .
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2
2 Cited Publications
Cat. No.: HY-P0276A
Synonyms: Gastric Inhibitory Peptide (GIP), human TFA
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

GIP, human TFA, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human TFA acts as an incretin hormone released from intestinal K cells in response to nutrient ingestion .
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2
2 Cited Publications
Cat. No.: HY-P0009A
CAS No.: 145672-81-7
Synonyms: SB-75 acetate
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology

Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research .
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