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Sincalide (Synonyms: Cholecystokinin octapeptide; CCK-8; SQ19844)

Cat. No.: HY-P0093
Handling Instructions

Sincalide (Cholecystokinin octapeptide) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is an agent that promotes gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. The hepatobiliary physiologic effect of Sincalide ammonium is to increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Sincalide Chemical Structure

Sincalide Chemical Structure

CAS No. : 25126-32-3

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1 mg USD 108 In-stock
Estimated Time of Arrival: December 31
5 mg USD 396 Get quote
10 mg USD 588 Get quote
25 mg USD 1140 Get quote
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Based on 1 publication(s) in Google Scholar

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Description

Sincalide (Cholecystokinin octapeptide) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is an agent that promotes gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. The hepatobiliary physiologic effect of Sincalide ammonium is to increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum[1][2].

Clinical Trial
Molecular Weight

1143.27

Formula

C₄₉H₆₂N₁₀O₁₆S₃

CAS No.

25126-32-3

Sequence

Asp-{SO3H-Tyr}-Met-Gly-Trp-Met-Asp-Phe-NH2

Sequence Shortening

D-{SO3H-Tyr}-MGWMDF-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Protect from light
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : 50 mg/mL (43.73 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.8747 mL 4.3734 mL 8.7468 mL
5 mM 0.1749 mL 0.8747 mL 1.7494 mL
10 mM 0.0875 mL 0.4373 mL 0.8747 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMF    90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.19 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

SincalideCholecystokinin octapeptideCCK-8SQ19844CCK8CCK 8SQ 19844SQ-19844OthersInhibitorinhibitorinhibit

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Product name:
Sincalide
Cat. No.:
HY-P0093
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