676 Results for "

human T-cell

" in MedChemExpress (MCE) Product Catalog:
Products (676)

676 Results for "human T-cell" in MCE Product Catalog:

24
24 Publications Verification
Cat. No.: HY-P7037
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T cell Growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In Regulation Of T-cell Clonal Expansion; TCGF; T-cell Growth Factor; Interleukin-2; Lymphokine
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13
13 Cited Publications
Cat. No.: HY-P7119
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB2; Transforming Growth Factor, Beta 2; Transforming Growth Factor Beta 2; BSC-1 cell Growth Inhibitor; Glioblastoma-Derived T-cell Suppressor Factor; TGF-Beta2; Transforming Growth Factor Beta-2 Proprotein; Polyergin; Prepro-Transforming Growth Factor
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8
8 Cited Publications
Cat. No.: HY-W107464
CAS No.: 2457232-14-1
Target:  

PDI

G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC50 of 0.07 μM for human G6PD. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells .
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7
7 Cited Publications
Cat. No.: HY-P70450
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL5; T-cell Specific Protein P288; Prev. D17S136E; C-C Motif Chemokine 5; Prev. SCYA5; MGC17164; TCP228; EoCP; SIS-Delta; Small Inducible Cytokine A5 (RANTES); RANTES; T-cell Specific RANTES Protein; SISd; T-cell-Specific Protein RANTES; Regulated Upon A
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7
7 Cited Publications
Cat. No.: HY-N7038
CAS No.: 9008-97-3
Synonyms: PHA-M
Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, is a T-cell activator. Phytohemagglutinin stimulates human mononuclear leukocytes, inducing the expression of ChAT mRNA and potentiating ACh synthesis. Phytohemagglutinin induces dose- and time-dependent toxicity in THP-1 monocytes/macrophages, alters cellular morphology, causes organelle dysfunction, and increases the expression of NF-κB, COX2, IL-1β .
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7
7 Cited Publications
Cat. No.: HY-145923
CAS No.: 2489404-97-7
Purity:  99.38%
Synonyms: ABBV-CLS-484
Target:  

Phosphatase STAT JAK

Research Areas:  

Cancer

Osunprotafib (ABBV-CLS-484) is an orally active and selective active site PTPN1 (IC50: 2.5 nM) and PTPN2(IC50: 1.8 nM) inhibitor. Osunprotafib has 6-8-fold weaker activity on PTPN9 and no detectable activity on SHP-1 or SHP-2. Osunprotafib increases the sensitivity of human cancer cell lines to IFNγ. Osunprotafib generates robust anti-tumor immunity by enhancing JAK-STAT signalling and reducing T cell dysfunction .
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7
7 Cited Publications
Cat. No.: HY-P7224
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; Lung Giant cell Carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; Neutrophil-Activating Peptide 1; MONAP; T-cell Chemotactic Factor; GCP-1; Interleukin 8; Monocyte-Derived Neutrophil Chemotactic Factor; Interleukin-8; Monocyte-Derived Neutrophil-Activating Peptide; Emoctakin; Granulocyte Chemotactic Protein 1; AMCF-I; Chemokine (C-X-C Motif) Ligand 8; B-ENAP; SCYB8; TSG-1; LYNAP; 3-10C; LUCT; K60; LECT; Small Inducible Cytokine Subfamily B, Member 8; IL-8; Beta-Thromboglobulin-Like Protein; GCP1; Neutrophil-Activating Protein 1; NAP1; C-X-C Motif Chemokine 8; NAF; C-X-C Motif Chemokine; Beta Endothelial cell-Derived Neutrophil Activating Peptide; Protein 3-10C; C-X-C Motif Chemokine Ligand 8; Lymphocyte Derived Neutrophil Activating Peptide
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6
6 Cited Publications
Cat. No.: HY-131140
CAS No.: 892686-59-8
Purity:  99.10%
Target:  

JAK STAT

Research Areas:  

Inflammation/Immunology Cancer

BD750, an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation, with IC50 values of 1.5 μM and 1.1 μM in mouse and human T cells, respectively .
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5
5 Cited Publications
Cat. No.: HY-P7037B
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL2; T cell Growth Factor; Interleukin 2; Aldesleukin; IL-2; Involved In Regulation Of T-cell Clonal Expansion; TCGF; T-cell Growth Factor; Interleukin-2; Lymphokine
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5
5 Cited Publications
Cat. No.: HY-113618A
CAS No.: 1219927-22-6
Research Areas:  

Cardiovascular Disease

RO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 hydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 hydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways .
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5
5 Cited Publications
Cat. No.: HY-113618B
CAS No.: 2309172-44-7
Purity:  98.21%
Research Areas:  

Cardiovascular Disease

RO2959 monohydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 monohydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 monohydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways .
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5
5 Cited Publications
Cat. No.: HY-P9901
CAS No.: 477202-00-9
Synonyms: MDX-010; BMS-734016

Target:  

CTLA-4

Research Areas:  

Cancer

Ipilimumab is a fully human monoclonal antibody IgG1κ that blocks the inhibitory receptor cytotoxic T lymphocyte antigen 4 (CTLA-4) on T cells. Ipilimumab can be used in unresectable or metastatic melanoma (MM) studies .
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5
5 Cited Publications
Cat. No.: HY-P1956
CAS No.: 70024-90-7
Synonyms: human serum albumin
HSA Protein (Human serum albumin) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ?) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant HSA Protein expressed in a microbial expression system.
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5
5 Cited Publications
Cat. No.: HY-N9965
CAS No.: 41263-94-9
Synonyms: 2'-FL
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines .
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4
4 Cited Publications
Cat. No.: HY-P7030
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2A
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4
4 Cited Publications
Cat. No.: HY-P7030A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10; TGIF; Interleukin 10; T-cell Growth Inhibitory Factor; IL-10; Interleukin-10; CSIF; Interleukin Family Protein; Cytokine Synthesis Inhibitory Factor; GVHDS; IL10A; IF2A
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CHO
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4
4 Cited Publications
Cat. No.: HY-P72975
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: DPP4; DPP IV; Prev. ADCP2; TP103; Prev. CD26; Post-Proline Dipeptidyl Aminopeptidase IV; Adenosine Deaminase Complexing Protein 2; Xaa-Pro-Dipeptidylaminopeptidase; T-cell Activation Antigen CD26; Gly-Pro Naphthylamidase; Dipeptidyl Peptidase IV; Dipeptid
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4
4 Cited Publications
Cat. No.: HY-P70569
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; Lung Giant cell Carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; Neutrophil-Activating Peptide 1; MONAP; T-cell Chemotactic Factor; GCP-1; Interleukin 8
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4
4 Cited Publications
Cat. No.: HY-B0735A
CAS No.: 67227-57-0
Synonyms: Fenoldopam methanesulfonate; SKF-82526 mesylate
Fenoldopam (SKF-82526) mesylate is a selective dopamine D1 receptor agonist. Fenoldopam mesylate binds to rat D1B dopamine receptors (Kd = 11 nM) and human D1A receptors (Kd = 17 nM) in COS-7 cell membranes expressing the cloned receptors. Fenoldopam mesylate modulates dopamine receptor expression, induces vasorelaxation in vascular tissues, reverses glomerular hyperfiltration in rat models, increases intracellular cAMP levels, promotes DARPP-32 phosphorylation in small cell lung cancer (SCLC) cells, inhibits cytokine secretion, and downregulates T cell activation markers in activated human T cells. Fenoldopam mesylate can be used for research on hypertension, acute kidney injury, psoriasis, and small cell lung cancer .
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4
4 Cited Publications
Cat. No.: HY-P7039
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL22; TIFa; Interleukin 22; IL-10-Related T-cell-Derived Inducible Factor; IL-TIF; Cytokine Zcyto18; ILTIF; Interleukin-22; IL-22; MGC79382; TIFIL-23; MGC79384; Zcyto18; IL-10-Related T-cell-Derived-Inducible Factor; IL-D110; Interferon 2B1; IL-21; ZCYTO1
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