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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
hypothalamic-pituitary-adrenocortical axis
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "hypothalamic-pituitary-adrenocortical axis" in MCE Product Catalog:
Cat. No.: HY-W009154
CAS No.: 6825-20-3
Cat. No.: HY-106898A
CAS No.: 136777-43-0
Target:
Research Areas:
Carvotroline hydrochloride is an antipsychotic agent and 5-HT2 receptor antagonist, with a Ki value of 211 nM for the 5-HT2 receptor. Carvotroline hydrochloride modulates the activity of the stress-related hypothalamic-pituitary-adrenal axis. Carvotroline hydrochloride exerts a stronger blocking effect on Apomorphine (HY-12723)-induced climbing behavior than on Apomorphine-induced stereotyped behavior. Carvotroline hydrochloride inhibits conditioned avoidance responses in rats and monkeys without inducing catalepsy. Carvotroline hydrochloride can be used in studies related to schizophrenia .
Cat. No.: HY-19682A
CAS No.: 68576-88-5
Target:
Research Areas:
Enciprazine dihydrochloride is an orally active non-benzodiazepine anxiolytic. Enciprazine dihydrochloride acts as an agonist of 5-HT1A receptor (5-HT1AR) and an antagonist of α1-adrenergic receptor (α1-adrenergic receptor) . Enciprazine dihydrochloride induces drug-related electroencephalogram changes by reducing the average power of δ waves and θ waves, and increasing the average power of α waves and fast β waves. Enciprazine dihydrochloride exhibits anti-aggressive activity, with only weak sedative and ataxic effects. Enciprazine dihydrochloride regulates plasma corticosterone levels and activates the hypothalamic-pituitary-adrenal axis. Enciprazine dihydrochloride can be used in research related to anxiety disorders, generalized anxiety syndrome and psychosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
