6825-20-3
Chemical Structure
3,6-Dibromocarbazole
- CAS No.: 6825-20-3
- Formula:C12H7Br2N
- Molecular Weight:325.00
IUPAC Name: 3,6-dibromo-9H-carbazole
InChIKey: FIHILUSWISKVSR-UHFFFAOYSA-N
SMILES: BrC1=CC(C2=C3C=CC(Br)=C2)=C(N3)C=C1
Biological Activity: 3,6-Dibromocarbazole is a glucocorticoid receptor (GR) inhibitor and Environmental pollutant. 3,6-Dibromocarbazole induces abnormal development of zebrafish embryos and disrupts the neurohormonal function of the hypothalamic-pituitary-adrenal axis in zebrafish larvae. 3,6-Dibromocarbazole increases the α-diversity of soil bacteria, alters community structure, enhances interspecific competition, regulates metabolic functions, and changes the abundance of genes related to nitrogen fixation, nitrification and carbon cycling. 3,6-Dibromocarbazole exerts endocrine-disrupting potential by interfering with the gluconeogenesis pathway[1][2].
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3,6-Dibromocarbazole | 99.94% | 3,6-Dibromocarbazole is a glucocorticoid receptor (GR) inhibitor and Environmental pollutant. 3,6-Dibromocarbazole induces abnormal development of zebrafish embryos and disrupts the neurohormonal function of the hypothalamic-pituitary-adrenal axis in zebrafish larvae. 3,6-Dibromocarbazole increases the α-diversity of soil bacteria, alters community structure, enhances interspecific competition, regulates metabolic functions, and changes the abundance of genes related to nitrogen fixation, nitrification and carbon cycling. 3,6-Dibromocarbazole exerts endocrine-disrupting potential by interfering with the gluconeogenesis pathway. | ||||||||||||||||||||
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3,6-Dibromocarbazole-d6 | 3,6-Dibromocarbazole-d6 is the deuterium labeled 3,6-Dibromocarbazole (HY-W009154). | |||||||||||||||||||||
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References
- [1]. Zou H, et al. In vitro, in vivo, and in silico evaluation of the glucocorticoid receptor antagonist activity of 3,6-dibromocarbazole. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023 Oct;180:114048. [Content Brief]
- [2]. Shi B, et al. 3,6-dibromocarbazole have a significant effect on diversity, community and function of soil microorganisms. Journal of hazardous materials. 2025 Sep 05;495:138962. [Content Brief]
