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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
imiquimod-induced psoriasis mouse model
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "imiquimod-induced psoriasis mouse model" in MCE Product Catalog:
Cat. No.: HY-136527
CAS No.: 2460133-35-9
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BMS-986251 is an orally active and selective RORγt inverse agonist with an EC50 of 12 nM for RORγt GAL4. BMS-986251 inhibits IL-17 with an EC50 of 24 nM in human whole blood assay. BMS-986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod-induced (HY-B0180) models (preclinical models of psoriasis) .
Cat. No.: HY-144265
CAS No.: 2768626-06-6
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PDE4-IN-5 (compound 33a) is a potent and selective PDE4 inhibitor (IC50=3.1 nM). PDE4-IN-5 has favorable skin permeability and a well-characterized binding mechanism. Anti-psoriasis effect .
Cat. No.: HY-187707
CAS No.: 108975-37-7
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MPiN is a KV1.3 potassium channel inhibitor. The IC50 values of MPiN for inhibiting Kv1.3 currents are 1.1 μM (at -90 mV) and 0.6 μM (at -35 mV). MPiN exhibits in vivo efficacy in a mouse psoriasis model. MPiN can be used for the research of psoriasis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
