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Results for "

interleukin-18

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

35

Recombinant Proteins

3

Antibodies

2

Oligonucleotides

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Cat. No. Compare Product Name Species Source Image
  • HY-P79202
    IL-18/IL-1F4 Protein, Porcine

    interleukin-18; IL-18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma; IGIF; interleukin 18

    		 Porcine E. coli
    IL-18/IL-1F4 protein is a pro-inflammatory cytokine that is critical in epithelial barrier repair and coordinates immune responses involving Th1 cells and NK cells. IL-18 binds to IL18R1 and IL18RAP to form a ternary complex that activates NF-κ-B and triggers the synthesis of inflammatory mediators. IL-18/IL-1F4 Protein, Porcine is the recombinant Porcine-derived IL-18/IL-1F4 protein, expressed by E. coli , with tag free.
  • HY-P706000
    IL-18 Protein, Rhesus Macaque

    interleukin-18; IFN-gamma-inducing factor; IL-18; IL-1 gamma; Igif; IL-1F4

    		 Rhesus Macaque E. coli
    IL-18 protein is a pro-inflammatory cytokine that is critically involved in epithelial barrier repair and regulates immune responses, especially Th1 cell and NK cell immune responses. IL-18 binds to IL18R1 and IL18RAP receptors to form a signaling ternary complex, activate NF-κ-B, and induce inflammatory mediators. IL-18 Protein, Rhesus Macaque is the recombinant Rhesus Macaque-derived IL-18 protein, expressed by E. coli.
  • HY-P73181
    IL-18 Protein, Mouse (solution)
    5 Publications Verification

    interleukin-18; IFN-gamma-inducing factor; IL-18; IL-1 gamma; Igif; IL-1F4

    		 Mouse E. coli
    IL-18 protein is a pro-inflammatory cytokine that plays an important role in epithelial barrier repair and immune response regulation by polarizing T helper 1 (Th1) cells and natural killer (NK) cells. After binding to IL18R1 and IL18RAP receptors, IL-18 forms a signaling ternary complex, activates NF-κ-B, and induces inflammatory mediators. IL-18 Protein, Mouse (solution) is the recombinant mouse-derived IL-18 protein, expressed by E. coli , with tag free.
  • HY-P70642
    IL-18 Protein, Mouse (His)
    1 Publications Verification

    interleukin-18; Il18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma; Igif

    		 Mouse E. coli
    IL-18 protein is a pro-inflammatory cytokine that plays an important role in epithelial barrier repair and immune response regulation by polarizing T helper 1 (Th1) cells and natural killer (NK) cells. After binding to IL18R1 and IL18RAP receptors, IL-18 forms a signaling ternary complex, activates NF-κ-B, and induces inflammatory mediators. IL-18 Protein, Mouse (His) is the recombinant mouse-derived IL-18 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P73182
    IL-18 Protein, Rhesus Macaque (His)

    interleukin-18; IFN-gamma-inducing factor; IL-18; IL-1 gamma; Igif; IL-1F4

    		 Rhesus Macaque E. coli
    IL-18 protein is a pro-inflammatory cytokine that is critically involved in epithelial barrier repair and regulates immune responses, especially Th1 cell and NK cell immune responses. IL-18 binds to IL18R1 and IL18RAP receptors to form a signaling ternary complex, activate NF-κ-B, and induce inflammatory mediators. IL-18 Protein, Rhesus Macaque (His) is the recombinant Rhesus Macaque-derived IL-18 protein, expressed by E. coli , with N-6*His, labeled tag.
  • HY-P70642AF
    Animal-Free IL-18 Protein, Mouse (His)

    interleukin-18; Il18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma; Igif

    		 Mouse E. coli
    IL-18 protein is a pro-inflammatory cytokine that plays an important role in epithelial barrier repair and immune response regulation by polarizing T helper 1 (Th1) cells and natural killer (NK) cells. After binding to IL18R1 and IL18RAP receptors, IL-18 forms a signaling ternary complex, activates NF-κ-B, and induces inflammatory mediators. Animal-Free IL-18 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-18 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.
  • HY-P71657
    IL-18 Protein, Dog (His)

    IL18; IGIF; interleukin-18; IL-18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma

    		 Dog E. coli
    IL-18 protein is a pro-inflammatory cytokine that is critical for epithelial barrier repair and immune regulation, especially in Th1 and NK cell responses. IL18R1 and IL18RAP combine to form a signaling ternary complex that activates NF-kappa-B and induces inflammatory mediators. IL-18 Protein, Dog (His) is the recombinant dog-derived IL-18 protein, expressed by E. coli , with N-His labeled tag.
  • HY-P70591A
    IL-18 Protein, Human (N-His)

    interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma; GIF; IL-18; IL-1g; IL1F4; MGC12320; IL18

    		 Human E. coli
    IL-18 protein is a pro-inflammatory cytokine that plays a critical role in epithelial barrier repair and polarized immune responses involving Th1 cells and NK cells. After binding to IL18R1 and IL18RAP, it forms a signaling ternary complex that activates NF-kappa-B, leading to the synthesis of inflammatory mediators. IL-18 Protein, Human (N-His) is the recombinant human-derived IL-18 protein, expressed by E. coli , with N-6*His labeled tag.
  • HY-P70591
    IL-18 Protein, Human
    4 Publications Verification

    interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma; GIF; IL-18; IL-1g; IL1F4; MGC12320; IL18

    		 Human E. coli
    IL-18 protein is a pro-inflammatory cytokine that plays a critical role in epithelial barrier repair and polarized immune responses involving Th1 cells and NK cells. After binding to IL18R1 and IL18RAP, it forms a signaling ternary complex that activates NF-kappa-B, leading to the synthesis of inflammatory mediators. IL-18 Protein, Human is the recombinant human-derived IL-18 protein, expressed by E. coli , with tag free.
  • HY-P70591G
    GMP IL-18 Protein, Human

    interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma; GIF; IL-18; IL-1g; IL1F4; MGC12320; IL18

    		 Human E. coli
    GMP IL-18 protein is a pro-inflammatory cytokine that plays a critical role in epithelial barrier repair and polarized immune responses involving Th1 cells and NK cells. After binding to IL18R1 and IL18RAP, it forms a signaling ternary complex that activates NF-kappa-B, leading to the synthesis of inflammatory mediators. GMP IL-18 Protein, Human is the recombinant human-derived GMP IL-18 protein, expressed by E. coli , with tag free.
  • HY-P700108AF
    Animal-Free IL-18 Protein, Human (His)

    interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma; GIF; IL-18; IL-1g; IL1F4; MGC12320; IL18

    		 Human E. coli
    IL-18 protein is a pro-inflammatory cytokine that plays a critical role in epithelial barrier repair and polarized immune responses involving Th1 cells and NK cells. After binding to IL18R1 and IL18RAP, it forms a signaling ternary complex that activates NF-kappa-B, leading to the synthesis of inflammatory mediators. Animal-Free IL-18 Protein, Human (His) is the recombinant human-derived animal-FreeIL-18 protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.
  • HY-P70760G
    GMP IL-18 Protein, Human (HEK293, His)

    interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; interleukin-1 gamma; IL-1 gamma; GIF; IL-18; IL-1g; IL1F4; MGC12320; IL18

    		 Human HEK293
    IL-18 protein is a pro-inflammatory cytokine that plays a critical role in epithelial barrier repair and polarized immune responses involving Th1 cells and NK cells. After binding to IL18R1 and IL18RAP, it forms a signaling ternary complex that activates NF-kappa-B, leading to the synthesis of inflammatory mediators. GMP IL-18 Protein, Human (HEK293, His) is the recombinant human-derived IL-18 protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P75848
    IL-18RAP Protein, Mouse (sf9, His)

    interleukin-18 receptor accessory protein; IL-18RAcP; AcPL; IL-18RAP; CD218b

    		 Mouse Sf9 insect cells
    IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators, regulation of the cytotoxic activity of NK cells and T cells, and differentiation and activation of both Th1 and Th2 cells. IL-18 signals through its specific cell surface receptor IL-18R, which comprises two subunits: IL-18Rα and IL-18R beta. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of NF- kβ.IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice. IL-18RAP Protein, Mouse (sf9, His) is a recombinant protein with a His label and is produced by Sf9 insect cells.
  • HY-P76993
    IL-18R alpha Protein, Canine (HEK293, His)

    interleukin-18 receptor 1; CDw218a; IL-1Rrp; IL-18R-alpha; CD218a

    		 Canine HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Canine (HEK293, His) is a recombinant protein with a His label that consists of 327 amino acids (M1-R327) and is produced by HEK293 cells.
  • HY-P77409
    IL-18RAP Protein, Rhesus Macaque (HEK293, His)

    interleukin-18 receptor accessory protein; CDw218b; IL-1R7; IL-18R-beta; CD218b

    		 Rhesus Macaque HEK293
    IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators, regulation of the cytotoxic activity of NK cells and T cells, and differentiation and activation of both Th1 and Th2 cells. IL-18 signals through its specific cell surface receptor IL-18R, which comprises two subunits: IL-18Rα and IL-18R beta. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of NF- kβ.IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice. IL-18RAP Protein, Rhesus Macaque (HEK293, His) is a recombinant protein with a His label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells.
  • HY-P76994
    IL-18R alpha Protein, Canine (HEK293, Fc)

    interleukin-18 receptor 1; CDw218a; IL-1Rrp; IL-18R-alpha; CD218a

    		 Canine HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Canine (HEK293, Fc) is a recombinant protein with a Fc label that consists of 327 amino acids (M1-R327) and is produced by HEK293 cells.
  • HY-P77408
    IL-18RAP Protein, Rhesus Macaque (HEK293, Fc)

    interleukin-18 receptor accessory protein; CDw218b; IL-1R7; IL-18R-beta; CD218b

    		 Rhesus Macaque HEK293
    IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators, regulation of the cytotoxic activity of NK cells and T cells, and differentiation and activation of both Th1 and Th2 cells. IL-18 signals through its specific cell surface receptor IL-18R, which comprises two subunits: IL-18Rα and IL-18R beta. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of NF- kβ.IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice. IL-18RAP Protein, Rhesus Macaque (HEK293, Fc) is a recombinant protein with a Fc label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells.
  • HY-P76424
    IL-18R alpha Protein, Rat (HEK293, His)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL1RRP; IL-18R-alpha; CD218a

    		 Rat HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Rat (HEK293, His) is a recombinant protein with a His label that consists of 326 amino acids (M1-G326) and is produced by HEK293 cells.
  • HY-P76423
    IL-18R alpha Protein, Rat (HEK293, Fc)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL1RRP; IL-18R-alpha; CD218a

    		 Rat HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Rat (HEK293, Fc) is a recombinant protein with hFc tag and is produced by HEK293 cells.
  • HY-P703778
    IL-18R alpha Protein, Cynomolgus (HEK293, His)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL1RRP; IL-18R-alpha; CD218a

    		 Cynomolgus HEK293
    IL-18R alpha Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-18R alpha protein, expressed by HEK293, with C-His tag.
  • HY-P76425
    IL-18R beta/IL-1R7 Protein, Human (HEK293, Fc)

    interleukin-18 receptor accessory protein; CDw218b; IL-1R7; IL-18R-beta; CD218b

    		 Human HEK293
    IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators, regulation of the cytotoxic activity of NK cells and T cells, and differentiation and activation of both Th1 and Th2 cells. IL-18 signals through its specific cell surface receptor IL-18R, which comprises two subunits: IL-18Rα and IL-18R beta. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of NF- kβ.IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice.IL-18R beta/IL-1R7 Protein, Human (HEK293, Fc) is a recombinant protein with a Fc label that is produced by HEK293 cells.
  • HY-P77406
    IL-18R alpha Protein, Rhesus macaque (HEK293, Fc)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL1RRP; IL-18R-alpha; CD218a

    		 Rhesus Macaque HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Rhesus macaque (HEK293, Fc) is a recombinant protein with a Fc label that consists of 315 amino acids (M1-K315) and is produced by HEK293 cells.
  • HY-P77407
    IL-18R alpha Protein, Rhesus macaque (HEK293, His)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL1RRP; IL-18R-alpha; CD218a

    		 Rhesus Macaque HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Cynomolgus (HEK293, His) is a recombinant protein with a His label that consists of 315 amino acids (M1-K315) and is produced by HEK293 cells.
  • HY-P75842
    IL-18R alpha Protein, Human (HEK293, Fc)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL-1Rrp; IL-18R-alpha; CD218a; IL18R1

    		 Human HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Human (HEK293, Fc) is a recombinant protein with a Fc label that consists of 329 amino acids (M1-R329) and is produced by HEK293 cells.
  • HY-P75843
    IL-18R alpha Protein, Human (HEK293, His)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL-1Rrp; IL-18R-alpha; CD218a; IL18R1

    		 Human HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Human (HEK293, His) is a recombinant protein with a His label that consists of 311 amino acids (A19-R329) and is produced by HEK293 cells.
  • HY-P75847
    IL-18R alpha Protein, Mouse (HEK293, His)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL-1Rrp; IL-18R-alpha; CD218a; IL18R1

    		 Mouse HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Mouse (HEK293, His) is a recombinant protein with a His label that is produced by HEK293 cells.
  • HY-P75845
    IL-18R alpha Protein, Mouse (HEK293, Fc)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL-1Rrp; IL-18R-alpha; CD218a; IL18R1

    		 Mouse HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Mouse (HEK293, Fc) is a recombinant protein with a Fc label and is produced by HEK293 cells.
  • HY-P75846
    IL-18R alpha Protein, Mouse (HEK293, His-Fc)

    interleukin-18 receptor 1; IL-18R1; CDw218a; IL-1Rrp; IL-18R-alpha; CD218a; IL18R1

    		 Mouse HEK293
    IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18. IL-18R alpha Protein, Mouse (HEK293, His-Fc) is a recombinant protein with a His-Fc label and is produced by HEK293 cells.
  • HY-P72573
    IL-18R beta/IL-1R7 Protein, Human (HEK293, His)

    interleukin-18 receptor accessory protein; IL-18RAcP; AcPL; CDw218b; IL-1RAcPL; IL-1R7; IL-18R-beta; CD218b

    		 Human HEK293
    IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators, regulation of the cytotoxic activity of NK cells and T cells, and differentiation and activation of both Th1 and Th2 cells. IL-18 signals through its specific cell surface receptor IL-18R, which comprises two subunits: IL-18Rα and IL-18R beta. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of NF- kβ.IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice. IL-18R beta/IL-1R7 Protein, Human (HEK293, His) is a recombinant protein with a His label that is produced by HEK293 cells.
  • HY-P705145
    IL-18R beta/IL-1R7 Protein, Human (Biotinylated, HEK293, His-Avi)

    interleukin-18 receptor accessory protein; IL-18RAcP; AcPL; CDw218b; IL-1RAcPL; IL-1R7; IL-18R-beta; CD218b

    		 Human HEK293
  • HY-P700742
    IL-18BP Protein, Cynomolgus (HEK293, His)

    IL-18BP; Igifbp; interleukin-18-binding protein

    		 Cynomolgus HEK293
    The IL-18BP protein is an inhibitor of IL-18, which binds to IL-18 and prevents IL-18 from binding to its receptor, thereby inhibiting IL-18-induced IFN-γ production. IL-18BP protein is constitutively expressed and secreted in monocytes. IFN-γ can enhance the expression of this protein. IL-18BP Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-18BP protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P75841
    IL-18BP Protein, Mouse (HEK293, His)
    5 Publications Verification

    interleukin-18-binding protein; IL-18BP; Tadekinig-alfa

    		Mouse HEK293
    IL-18BP protein regulates immune processes by binding to interleukin-18 (IL-18), inhibiting its activity. This interaction positions IL-18BP as a key inhibitor of the early TH1 cytokine response, emphasizing its role in immune modulation and potential contribution to regulating inflammatory responses. IL-18BP Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-18BP protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P72575
    IL-18BP Protein, Human (HEK293, hFc)
    1 Publications Verification

    interleukin-18-binding protein; IL-18BP; Tadekinig-alfa

    		Human HEK293
    IL-18BP Protein belongs to immunoglobulin superfamily that bind to IL-18 and inhibits its activity. IL-18BP Protein functions as an inhibitor of the Th1 cytokine response. IL-18BP Protein, Human (HEK293, hFc) is the recombinant human-derived IL-18BP protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P701010
    IL-18BP Protein, Cynomolgus (Biotinylated, HEK293, His)

    IL-18BP; Igifbp; interleukin-18-binding protein

    		 Cynomolgus HEK293
    The IL-18BP protein is an inhibitor of IL-18, which binds to IL-18 and prevents IL-18 from binding to its receptor, thereby inhibiting IL-18-induced IFN-γ production. IL-18BP protein is constitutively expressed and secreted in monocytes. IFN-γ can enhance the expression of this protein. IL-18BP Protein, Cynomolgus (Biotinylated, HEK293, His) is the recombinant cynomolgus-derived IL-18BP protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P72574
    IL-18BP Protein, Mouse (HEK293, Fc)

    interleukin-18-binding protein; IL-18BP; IL18 BPd; Igifbp

    		 Mouse HEK293
    IL-18BP protein regulates immune processes by binding to interleukin-18 (IL-18), inhibiting its activity. This interaction positions IL-18BP as a key inhibitor of the early TH1 cytokine response, emphasizing its role in immune modulation and potential contribution to regulating inflammatory responses. IL-18BP Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IL-18BP protein, expressed by HEK293 , with C-hFc labeled tag.

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