NLRP3-IN-77
NLRP3-IN-77 (Compound 7n) is a potent NLRP3 inflammasome inhibitor. NLRP3-IN-77 inhibits the viability of THP-1 cells with an IC50 value of 5.36 nM. NLRP3-IN-77 can effectively reduce the secretion of interleukin-1β (IL-1β) and interleukin-18 (IL-18). NLRP3-IN-77 is promising for research of diseases related to the abnormal activation of the NLRP3 inflammasome, such as cancer and inflammatory diseases.
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- CAS. Nr.: 2924547-57-7
- Formel: C28H29N3O3S
- Molecular Weight:487.61
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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IL-1β |
NLRP3 inflammasome |
Chemical Information
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CAS. Nr. 2924547-57-7
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Molecular Weight 487.61
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Formel C28H29N3O3S
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SMILES
O=S(N1[C@@H](CC2=CC=CC=C2C1)C(NC3=C4C(CCC4)=CC5=C3CCC5)=O)(C6=CC=C(C=C6)N)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
NLRP3-IN-77 Related Classifications
HY-171589 Related Classifications
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