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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
isoprenoids
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "isoprenoids" in MCE Product Catalog:
2
Research Areas:
Risedronic acid (Risedronate) sodium, a bisphosphonate, is a potent anti-resorption agent that inhibits osteoclast-mediated bone resorption and changes the bone metabolism. Risedronic acid sodium suppresses osteoblast differentiation and induced caspase- and isoprenoid depletion-dependent apoptosis. Risedronic acid sodium inhibits blood stages of Plasmodium falciparum (IC50 of 20.3 μM). Risedronic acid sodium inhibits the transfer of the farnesyl pyrophosphate group to parasite proteins .
Cat. No.: HY-130573A
CAS No.: 1186-30-7
Synonyms: Dimethylallyl diphosphate triammonium
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DMAPP (Dimethylallyl diphosphate) triammonium is an isoprenoid precursor. DMAPP triammonium, as an isomer of isopentenyl pyrophosphate (IPP), exists in virtually all life forms .
Synonyms: Geranyl pyrophosphate triammonium
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Cat. No.: HY-113037
CAS No.: 13058-04-3
Synonyms: (E/Z)-Farnesyl diphosphate
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Endogenous metabolite Disease Research Fields
Target:
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Plants Maclurodendron oligophlebium (Merrill) T. G. Hartley Endogenous metabolite Disease Research Fields Salicaceae
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Synonyms: (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium
Category:
Cat. No.: HY-N0424
CAS No.: 84605-18-5
Synonyms: Cyclogalegigenin
Category:
Triterpenes Leguminosae Anti-aging Terpenoids Other Diseases Plants Disease Research Fields Astragalus galegiformis
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Cat. No.: HY-156202
CAS No.: 35750-48-2
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Geranylgeranoic acid (Compound 5) is inhibits lysine-specific demethylase 1 (LSD1) with an IC50 value of 46.97 µM. Geranylgeranoic acid induces apoptosis via loss of the mitochondrial membrane potential and activation of interleukin-1β-converting enzyme (ICE) and cysteine protease precursor 32 (CPP32) in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes. Geranylgeranoic acid an isoprenoid with anticancer activity, which is found in S. chinensis .
Cat. No.: HY-N8092
CAS No.: 99217-64-8
Category:
Flavonoids Leguminosae Flavonones Phenols Polyphenols Plants Sophora flavescens Aiton Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-19671
CAS No.: 126411-13-0
Synonyms: SR-45023A; SR 9223i; SK&F-99085
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Apomine (SR-45023A) is an orally active antineoplastic agent that inhibits the mevalonate/isoprenoid pathway in cholesterol synthesis. Apomine can accelerate the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR). Apomine can also inhibit the growth of various types of cancer cells, including lung cancer, colon cancer, breast cancer, and skin cancer. Apomine is able to induce apoptosis in tumor cell lines derived from leukemia, colon cancer, liver cancer, ovarian cancer, and breast cancer .
Cat. No.: HY-133927
CAS No.: 2361137-98-4
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(2E,6E)-3,7-Dimethyltrideca-2,6-dien-12-yn-1-ol is a isoprenoid analogue . (2E,6E)-3,7-Dimethyltrideca-2,6-dien-12-yn-1-ol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-155744
CAS No.: 1411977-91-7
Synonyms: LCB14-0536
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Acetylene-PEG3-MMAF-OMe (LCB14-0536) is a protein-active agent conjugate. Acetylene-PEG3-MMAF-OMe can be recognized by isoprenoid transferase . Acetylene-PEG3-MMAF-OMe is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-W717654
CAS No.: 190079-18-6
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1-Deoxy-D-xylulose 5-phosphate (DXP) is a biosynthetic precursor to isoprenoids, thiamin (vitamin B1), and pyridoxol (vitamin B6). 1-Deoxy-D-xylulose 5-phosphate can be utilized in metabolic research .
Target:
Cat. No.: HY-101021
CAS No.: 26166-39-2
Synonyms: Ilicicolin D
Category:
Anti-inflammation/Immunoregulatory Plants Disease Research Other Antibiotics other families Microorganisms Antibiotics Phenols Polyphenols Anticancer Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-128044
CAS No.: 149759-96-6
Synonyms: B581
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Ftase inhibitor I (B581) is a potent, selective and peptidomimetic farnesyl transferase (FTase) inhibitor. Ftase inhibitor I shows selectivity for FTase over geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras) .
Cat. No.: HY-169233
CAS No.: 2650073-66-6
MED6-189, a kalihinol analog, disrupts apicoplast function and vesicular trafficking in P. falciparum malaria (IC50 < 50 nM). MED6-189 targets the apicoplast, a nonphotosynthetic plastid found in most Apicomplexa parasites that is crucial for the synthesis of isoprenoids .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
