Ftase inhibitor I
Ftase inhibitor I (B581) is a potent, selective and peptidomimetic farnesyl transferase (FTase) inhibitor. Ftase inhibitor I shows selectivity for FTase over geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras).
For research use only. We do not sell to patients.
- CAS No.: 149759-96-6
- Formula: C22H38N4O3S2
- Molecular Weight:470.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Ftase inhibitor I (B581) inhibits the ability of only Ras-F-transformed cells, but not geranylgeranyl isoprenoid (Ras-GG) or the fatty acid myristate (Myr-Ras)- (or Raf-) transformed cells, to grow in soft agar[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 149759-96-6
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Molecular Weight 470.69
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Formula C22H38N4O3S2
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SMILES
CSCC[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC[C@@H](NC[C@@H](N)CS)C(C)C)=O
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Synonyms
B581
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)