2 Results for "

microtubule-gliding activity

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "microtubule-gliding activity" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-122632
CAS No.: 1370554-01-0
Purity:  99.36%
Target:  

Hedgehog

Research Areas:  

Cancer

Ciliobrevin D is a cell-permeable, reversible and specific inhibitor of AAA+ ATPase motor cytoplasmic dynein. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation. Ciliobrevin D inhibits dynein-dependent microtubule gliding and ATPase activity in vitro .
loading...
    loading...
Cat. No.: HY-121816
CAS No.: 68705-66-8
Kolaflavanone is an biflavonoid allosteric inhibitor of Eg5. Kolaflavanone inhibits the ATPase and tyrosinase activities of Eg5 under both basal and microtubule-activated conditions, suppresses microtubule sliding activity, binds to the L5/α2/α3 allosteric pocket of Eg5, induces conformational changes of Eg5 and microtubule dissociation, interacts with aldehyde dehydrogenase, inhibits the ATPase activity of kinesin-1, and binds to HSA via pH-dependent forces. Kolaflavanone exhibits antihepatotoxic activity and can be used in studies related to Phalloidin (HY-P0028)-induced liver injury .
loading...
    loading...