2. Natural Products
  3. Plants
  4. Guttiferae
  5. Garcinia kola Heckel

Garcinia kola Heckel

Garcinia kola Heckel (5):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-121816
    Kolaflavanone 68705-66-8
    Kolaflavanone is an allosteric inhibitor of Eg5. Kolaflavanone inhibits the ATPase and tyrosinase activities of Eg5 under both basal and microtubule-activated conditions, suppresses microtubule sliding activity, binds to the L5/α2/α3 allosteric pocket of Eg5, induces conformational changes of Eg5 and microtubule dissociation, interacts with aldehyde dehydrogenase, inhibits the ATPase activity of kinesin-1, and binds to HSA via pH-dependent forces. Kolaflavanone exhibits antihepatotoxic activity and can be used in studies related to Phalloidin (HY-P0028)-induced liver injury.
    Kolaflavanone
  • HY-N17652
    13′-Hydroxy-δ-tocopherol 1308347-24-1
    13′-Hydroxy-δ-tocopherol is a metabolite of long-chain vitamin E. 13′-Hydroxy-δ-tocopherol can induces cells apoptosis and minor reduction in mitochondrial membrane potential. 13′-Hydroxy-δ-tocopherol can be used for the research of hepatocellular carcinoma.
    13′-Hydroxy-δ-tocopherol
  • HY-N17653
    13'-Carboxy-δ-tocopherol 1160974-35-5
    13'-Carboxy-δ-tocopherol is a metabolite of long-chain vitamin E.13'-Carboxy-δ-tocopherol exhibits antiproliferative properties in cancer cells. 13'-Carboxy-δ-tocopherol activates caspase-3, caspase-9, causes PARP-1 cleavage, reduces mitochondrial membrane potential, increases ROS formation, and drives apoptosis.13'-Carboxy-δ-tocopherol can be used for the research of hepatocellular carcinoma.
    13'-Carboxy-δ-tocopherol
  • HY-N17629
    13'-Carboxy-α-tocopherol 1160974-37-7
    13'-Carboxy-α-tocopherol is a vitamin E derivative and antiproliferative agent. 13'-Carboxy-α-tocopherol inhibits proliferation of glioma cancer cells. 13'-Carboxy-α-tocopherol can be used for the research of glioma.
    13'-Carboxy-α-tocopherol
  • HY-Z11709
    13-Hydroxy-alpha-tocopherol 1160974-39-9
    13-Hydroxy-alpha-tocopherol is a fat-soluble vitamin E derivative and anticancer agent with antioxidant and antiproliferative activities. 13-Hydroxy-alpha-tocopherol scavenges peroxyl free radicals and protects polyunsaturated fatty acids from oxidative damage. 13-Hydroxy-alpha-tocopherol not only inhibits the growth of glioma cancer cells, but its deficiency is also closely associated with recurrent miscarriage, embryonic growth retardation and death. Clinical observations show that the expression of 13-Hydroxy-alpha-tocopherol is downregulated in the follicular fluid of patients with recurrent miscarriage. 13-Hydroxy-alpha-tocopherol has important application potential in the research of recurrent miscarriage and glioma.
    13-Hydroxy-alpha-tocopherol