5 Results for "

muscle-wasting diseases

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "muscle-wasting diseases" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99388
CAS No.: 1429201-24-0
Synonyms: REGN-1033; SAR391786

Target:  

TGF-beta/Smad

Research Areas:  

Inflammation/Immunology

Trevogrumab (REGN-1033) is a monoclonal antibody targeting GDF8 (growth differentiation factor 8, also known as myostatin). Trevogrumab is used in research on muscle wasting conditions, including disuse atrophy, chronic diseases, and changes in food and nutrient intake .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P99370
CAS No.: 1391726-30-9
Synonyms: LY2495655; Anti-GDF8 / Myostatin Reference Antibody (landogrozumab)

Target:  

TGF-beta/Smad

Research Areas:  

Inflammation/Immunology Cancer

Landogrozumab (LY2495655) is an humanized anti-myostatin monoclonal antibody. Landogrozumab effectively improves muscle volume, hand grip strength and function. Landogrozumab can be used for the research of muscle wasting disease .
loading...
    loading...
Cat. No.: HY-111044
CAS No.: 944919-15-7
Target:  

Androgen Receptor

Research Areas:  

Cancer

(+)-JNJ-37654032 is an orally active and selective androgen receptor modulator. (+)-JNJ-37654032 can be used in the study of muscle-wasting diseases .
loading...
    loading...
Cat. No.: HY-111203
CAS No.: 886208-76-0
Synonyms: MW189; MW01-6-189WH
TT-301 is a small-molecule immunomodulator capable of penetrating the blood-brain barrier. TT-301 exerts neuroprotective effects by binding to IL-1β, downregulating STAT3 expression, and modulating the JAK-STAT signaling pathway, thereby inhibiting microglial activation and the release of proinflammatory mediators, and alleviating neuroinflammation and brain edema. TT-301 is used in research on traumatic brain injury, intracerebral hemorrhage, subarachnoid hemorrhage, muscle wasting and atrophy, and periodontal disease .
loading...
    loading...
Cat. No.: HY-111203A
CAS No.: 1346545-21-8
Synonyms: MW189 hydrochloride; MW01-6-189WH hydrochloride
TT-301 hydrochloride is a small-molecule immunomodulator capable of penetrating the blood-brain barrier. TT-301 hydrochloride exerts neuroprotective effects by binding to IL-1β, downregulating STAT3 expression, and modulating the JAK-STAT signaling pathway, thereby inhibiting microglial activation and the release of proinflammatory mediators, and alleviating neuroinflammation and brain edema. TT-301 hydrochloride is used in research on traumatic brain injury, intracerebral hemorrhage, subarachnoid hemorrhage, muscle wasting and atrophy, and periodontal disease .
loading...
    loading...