25 Results for "

mycophenolic

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "mycophenolic" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-B0421
CAS No.: 24280-93-1
Synonyms: Mycophenolate
Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 µM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects .
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14
14 Publications Verification
Cat. No.: HY-B0421A
CAS No.: 37415-62-6
Synonyms: Mycophenolate sodium
Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 µM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects .
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13
13 Cited Publications
Cat. No.: HY-B0199
CAS No.: 128794-94-5
Synonyms: RS 61443; TM-MMF
Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation .
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1
1 Cited Publications
Cat. No.: HY-B0421S
CAS No.: 1185242-90-3
Synonyms: Mycophenolate-d3
Mycophenolic acid-d3 (Mycophenolate-d3) is deuterium labeled Mycophenolic acid (HY-B0421). Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects.
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Cat. No.: HY-137301
CAS No.: 31528-44-6
Purity:  98.65%
Target:  

Drug Metabolite

Research Areas:  

Cancer

Mycophenolic acid glucuronide is a metabolite of the immunosuppressant mycophenolic acid (MPA). Mycophenolic acid glucuronide shows anti-tumor activity and can be used in adenocarcinoma research .
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Cat. No.: HY-B0421R
CAS No.: 24280-93-1
Synonyms: Mycophenolate (Standard)
Mycophenolic acid (Standard) is the analytical standard of Mycophenolic acid. This product is intended for research and analytical applications. Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM.?Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects .
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Cat. No.: HY-113972
CAS No.: 31858-66-9
Purity:  ≥99.0%
Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae .
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Cat. No.: HY-118917
CAS No.: 297730-05-3
Target:  

IMPDH

Research Areas:  

Inflammation/Immunology

VX-148 is an orally active immunosuppressant, which is a non-competitive inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor with Ki values for IMPDH Ⅱ and IMPDH Ⅰ of 6 and 14 nM respectively. VX-148 can significantly inhibit the proliferation of human peripheral blood mononuclear cells (PBMC) stimulated by T-cell mitogen (PHA) or B-cell mitogen (SPAS). VX-148 has high selectivity for lymphocytes (such as L1210, Jurkat T cells, and Raji B cells), but has no significant toxicity to non-lymphoid cells. VX-148 can inhibit antibody responses in mouse models and significantly prolong the survival time of transplanted skin in allogeneic skin transplantation models. VX-148 can be used in the research of autoimmune diseases (such as rheumatoid arthritis, psoriasis) and organ transplantation anti-rejection .
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Cat. No.: HY-B0421S2
CAS No.: 1202866-92-9
Synonyms: Mycophenolate-13C17
Mycophenolic acid-13C17 (Mycophenolate-13C17) is the 13C labeled Mycophenolic acid (HY-B0421). Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects.
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Cat. No.: HY-B0421AR
CAS No.: 37415-62-6
Synonyms: Mycophenolate sodium (Standard)
Mycophenolic acid (sodium) (Standard) is the analytical standard of Mycophenolic acid (sodium). This product is intended for research and analytical applications. Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects .
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Cat. No.: HY-133778
CAS No.: 33431-38-8
Target:  

Drug Intermediate

Research Areas:  

Others

O-Desmethyl mycophenolic acid methyl ester is an intermediate in the synthesis of Mycophenolic acid .
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Cat. No.: HY-137301S
Mycophenolic acid glucuronide-d3 is the deuterium labeled Mycophenolic acid glucuronide .
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Cat. No.: HY-150533S
CAS No.: 1261432-16-9
(E/Z)-Mycophenolic Acid- 13C,d3 is the deuterium and 13C labeled (E/Z)-Mycophenolic Acid .
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Cat. No.: HY-113972A
CAS No.: 24243-40-1
Target:  

Drug Isomer

Research Areas:  

Inflammation/Immunology

(E/Z)-Methyl mycophenolate is a racemic compound of (Z)-Methyl mycophenolate and (E)-Methyl mycophenolate isomers. Methyl mycophenolate is a methyl ester of mycophenolic acid. Methyl mycophenolate can be used to synthesize mycophenolic acid β-D-glucuronide and phenolic glycosides .
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Cat. No.: HY-108416
CAS No.: 27979-57-3
Purity:  99.82%
Target:  

Drug Intermediate

Research Areas:  

Others

5,7-Dihydroxy-4-methylphthalide is a key intermediate in the synthesis of Mycophenolic acid and a secondary metabolite of Aspergillus flavus .
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Cat. No.: HY-W700289
CAS No.: 55533-52-3
Mycophenolic acid phenolic β-D-glucoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
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Cat. No.: HY-167927S
Mycophenolic Acid-d3 Acyl-Beta-D-glucuronide is the deuterium labeled Mefuparib (HY-167927). Mefuparib (CVL218) is a poly ADP-ribose polymerase (PARP) inhibitor used in cancer research that exhibits potent brain penetration due to its high protein binding.
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Cat. No.: HY-167926S
Mycophenolic Acid-d3 beta-D-Glucuronide is the deuterium labeled 3-Bromo-4,5-dihydroxybenzoic acid methyl ester (HY-167926). 3-Bromo-4,5-dihydroxybenzoic acid methyl ester is a marine-derived natural product known for its biological activity, specifically showcasing antioxidant properties and potential therapeutic applications against oxidative stress-related diseases.
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Cat. No.: HY-N15730
CAS No.: 172608-85-4
3-Hydroxymycophenolic acid (Compound 5) is a microbial transformation product of Mycophenolic acid (HY-B0421) by Cunninghamella echinulata. 3-Hydroxymycophenolic acid has low cytotoxicity against AGS cells and fibroblasts. 3-Hydroxymycophenolic acid can be used for immune-mediated renal diseases research .
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Cat. No.: HY-137238
CAS No.: 32483-51-5
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Ethyl mycophenolate is a potential impurity found in commercial preparations of the mycophenolic acid prodrug mycophenolate mofetil.
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