3 Results for "

myometrial contractions

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "myometrial contractions" in MCE Product Catalog:

Cat. No.: HY-P4160
CAS No.: 634586-40-6
Synonyms: THG113.31; ILGHXDYK
Research Areas:  

Endocrinology

PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor. PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca 2+-dependent large-conductance K +-channel in human myometrial cells .
loading...
    loading...
Cat. No.: HY-P2786A
CAS No.: 741738-57-8
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Phrixotoxin 2 is a Kv4 family potassium channel inhibitor, with Ki values in rats of 120 nM for Kv4.2, 110 nM for Kv4.3, and 230 nM for Kv4.1. Phrixotoxin 2 mediates voltage-dependent inhibition of Kv4.2 and Kv4.3 currents, and voltage-independent inhibition of Kv4.1 currents. Phrixotoxin 2 fails to inhibit A-type K + currents in visceral dorsal root ganglion neurons. Phrixotoxin 2 induces contraction of non-pregnant uterine smooth muscle and triggers orofacial cold hyperalgesia in rats. Phrixotoxin 2 can distinguish the contribution of Kv4 subunits to A-type K + currents in different subsets of sensory neurons. Phrixotoxin 2 can be used in research related to chronic pain and trigeminal neuropathic pain .
loading...
    loading...
Cat. No.: HY-122638
CAS No.: 1214573-32-6
Target:  

Potassium Channel

Research Areas:  

Others

MRT2000769 is a Kir7.1 inhibitor with an IC50 of 2 μM. MRT2000769 induces sustained contractions in the uterine muscle of pregnant mice. MRT2000769 is applicable for the research of postpartum hemorrhage .
loading...
    loading...