13120 Results for "

p-

" in MedChemExpress (MCE) Product Catalog:
Products (13120)

13120 Results for "p-" in MCE Product Catalog:

261
261 Publications Verification
Cat. No.: HY-P0175
CAS No.: 1236188-16-1
Synonyms: 740YPDGFR; PDGFR 740Y-P
Target:  

PI3K Autophagy

Research Areas:  

Cancer

740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .
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33
33 Cited Publications
Cat. No.: HY-P0201
CAS No.: 33507-63-0
Synonyms: Neurokinin P
Substance P (Neurokinin P) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
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33
33 Cited Publications
Cat. No.: HY-P0201A
CAS No.: 148470-19-3
Synonyms: Neurokinin P TFA
Substance P TFA (Neurokinin P TFA) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .
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28
28 Cited Publications
Cat. No.: HY-15667
CAS No.: 882257-11-6
Purity:  99.90%
Synonyms: P5091
Target:  

Deubiquitinase

Research Areas:  

Cancer

P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with an EC50 of 4.2 μM.
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28
28 Cited Publications
Cat. No.: HY-P70568
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial Hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
Source:  
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27
27 Cited Publications
Cat. No.: HY-P73243
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INS; Proinsulin; Prev. IDDM1; PNDM4; Prev. IDDM2; IDDM; Insulin-Dependent Diabetes Mellitus 2; ILPR; Preproinsulin; IRDN; Insulin; MODY10
Species:  
Source:  
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26
26 Cited Publications
Cat. No.: HY-P70460
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial Hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
Source:  
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24
24 Cited Publications
Cat. No.: HY-13865
CAS No.: 1247819-59-5
Purity:  98.07%
Target:  

Deubiquitinase

Research Areas:  

Cancer

P 22077 is a cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with an EC50 of 8.01 μM. P 22077 also inhibits USP47 with an EC50 of 8.74 μM.
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22
22 Cited Publications
Cat. No.: HY-P80622
Synonyms: CASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-F, IHC-P, ELISA

Reactivity:  

Human, Mouse

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21
21 Cited Publications
Cat. No.: HY-108496
CAS No.: 26993-30-6
Purity:  ≥99.0%
Synonyms: S1P
Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca 2+ as an extracellular ligand for G protein-coupled receptors . Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids . Sphingosine-1-phosphate stimulates the DNA synthesis, cell proliferation and migration .
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20
20 Cited Publications
Cat. No.: HY-W010968
CAS No.: 149022-20-8
Synonyms: A-5'-P sodium hydrate; AMP sodium hydrate; Adenosine 5'-monophosphate sodium hydrate
5'-Adenylic acid (sodium hydrate) (A-5'-P (sodium hydrate); AMP (sodium hydrate); Adenosine 5'-monophosphate (sodium hydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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19
19 Cited Publications
Cat. No.: HY-P0118
CAS No.: 272105-42-7
Synonyms: P144
Research Areas:  

Cancer

Disitertide (P144) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide (P144) is also a PI3K inhibitor and an apoptosis inducer .
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17
17 Cited Publications
Cat. No.: HY-P72795
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL13; MGC116789; Interleukin 13; ALRH; IL-13; BHR1; Interleukin-13; Bronchial Hyperresponsiveness-1 (Bronchial Asthma); P600; Allergic Rhinitis; MGC116786; NC30; MGC116788
Species:  
Source:  
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15
15 Cited Publications
Cat. No.: HY-12839
CAS No.: 1006378-90-0
Purity:  99.58%
Target:  

p38 MAPK Autophagy

Research Areas:  

Inflammation/Immunology

p38 MAPK-IN-1 (Compound 4) is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM. p38 MAPK-IN-1 shows sustained levels, low clearance and good bioavailability.
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13
13 Cited Publications
Cat. No.: HY-100237
CAS No.: 222716-34-9
Purity:  99.07%
Research Areas:  

Cancer

SZL P1-41 is a specific Skp2 inhibitor, binds to the F-box domain of Skp2 to prevent Skp1 association and Skp2 SCF complex formation. SZL P1-41, like Skp2 deficiency, augments p27-mediated apoptosis/senescence, while it impairs Akt-driven glycolysis. Anti-tumor activities .
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13
13 Cited Publications
Cat. No.: HY-100609
CAS No.: 134865-74-0
Purity:  99.90%
Target:  

Melatonin Receptor

Research Areas:  

Neurological Disease

4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist. 4-P-PDOT is >300-fold more selective for MT2 than MT1. 4-P-PDOT significantly counteracts Melatonin-mediated antioxidant effects (GSH/GSSG ratio, phospho-ERK, Nrf2 nuclear translocation, Nrf2 DNA-binding activity) .
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12
12 Cited Publications
Cat. No.: HY-146245
CAS No.: 202668-42-6
Purity:  96.86%
Synonyms: CpG 1826
ODN 1826 is a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist. ODN 1826 induces NO and iNOS production and enhances Apoptosis. ODN 1826 enhances immune surveillance. ODN 1826 increases aortic atherosclerotic plaque size. ODN 1826 has antitumor activity against lung cancer, glioma and melanoma .
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11
11 Cited Publications
Cat. No.: HY-148905
CAS No.: 6283-24-5
Purity:  99.07%
p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP). P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction. p-Aminophenylmercuric acetate promotes the shedding of betacellulin precursor (pro-BTC). p-Aminophenylmercuric acetate influences the binding of agonists and antagonists to the opiate receptor .
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10
10 Cited Publications
Cat. No.: HY-15976
CAS No.: 301353-96-8
Target:  

Others

Research Areas:  

Neurological Disease

P7C3 is an orally bioavailable and blood-brain barrier penetrant aminopropyl carbazole, with neuroprotective effects. P7C3 can be used for the research of neurodegenerative diseases, including Parkinson's disease .
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9
9 Cited Publications
Cat. No.: HY-15526
CAS No.: 851546-61-7
Purity:  99.79%
Synonyms: P-Selectin Inhibitor
Target:  

P-selectin

Research Areas:  

Cancer

PSI-697 is an oral P-selectin inhibitor with an IC50 of 125 μM .
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