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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
pharmacological chaperone
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "pharmacological chaperone" in MCE Product Catalog:
Synonyms: D-Isofagomine; Isofagomine
Target:
Research Areas:
Afegostat is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .
Synonyms: D-Isofagomine D-Tartrate; Isofagomine D-Tartrate
Target:
Research Areas:
Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .
Cat. No.: HY-121764
CAS No.: 884538-31-2
Target:
Research Areas:
MPCI is a cell-permeant MC4R-selective ligand with pharmacological chaperone activity. MPCI is a MC4R antagonist with a Ki value of 0.218 μM on HEK293 cells expressing hMC4R. MPCI can be used for the research of MC4R-deficient obesity .
Cat. No.: HY-178202
CAS No.: 2734265-58-6
Target:
Research Areas:
5-C-phenethyl-DNJ is a selective α-glucosidase GAA inhibitor, with its Ki value for rhGAA being 0.81 μM. 5-C-phenethyl-DNJ exhibits extremely high selectivity for GANAB, GBA1, and GBA2. 5-C-phenethyl-DNJ can be used for the study of Pompe disease .
Cat. No.: HY-14829B
CAS No.: 919364-56-0
Synonyms: AT 2101; D-Isofagomine tartrate; Isofagomine tartrate
Target:
Research Areas:
Afegostat tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .
Cat. No.: HY-14829H
CAS No.: 1084896-50-3
Target:
Research Areas:
Afegostat TFA is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
