Afegostat D-Tartrate
Based on 1 Customer Validation
Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 957230-65-8
- Formula: C10H19NO9
- Molecular Weight:297.26
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
GCase[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 957230-65-8
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Appearance Solid
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Molecular Weight 297.26
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Formula C10H19NO9
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Color White to yellow
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SMILES
OC[C@@H]1[C@H]([C@@H](CNC1)O)O.OC([C@@H](O)[C@H](O)C(O)=O)=O
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Synonyms
D-Isofagomine D-Tartrate; Isofagomine D-Tartrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H2O : ≥ 50 mg/mL (168.20 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.3641 mL | 16.8203 mL | 33.6406 mL | 84.1015 mL |
| 5 mM | 0.6728 mL | 3.3641 mL | 6.7281 mL | 16.8203 mL | |
| 10 mM | 0.3364 mL | 1.6820 mL | 3.3641 mL | 8.4101 mL | |
| 15 mM | 0.2243 mL | 1.1214 mL | 2.2427 mL | 5.6068 mL | |
| 20 mM | 0.1682 mL | 0.8410 mL | 1.6820 mL | 4.2051 mL | |
| 25 mM | 0.1346 mL | 0.6728 mL | 1.3456 mL | 3.3641 mL | |
| 30 mM | 0.1121 mL | 0.5607 mL | 1.1214 mL | 2.8034 mL | |
| 40 mM | 0.0841 mL | 0.4205 mL | 0.8410 mL | 2.1025 mL | |
| 50 mM | 0.0673 mL | 0.3364 mL | 0.6728 mL | 1.6820 mL | |
| 60 mM | 0.0561 mL | 0.2803 mL | 0.5607 mL | 1.4017 mL | |
| 80 mM | 0.0421 mL | 0.2103 mL | 0.4205 mL | 1.0513 mL | |
| 100 mM | 0.0336 mL | 0.1682 mL | 0.3364 mL | 0.8410 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.