Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
piperazine derivative
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "piperazine derivative" in MCE Product Catalog:
Cat. No.: HY-W002603
CAS No.: 31166-44-6
Target:
Research Areas:
Cyclizine, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine can be used for the research of nausea, vomiting, and dizziness .
Cat. No.: HY-W011726
CAS No.: 38869-47-5
Synonyms: piperazine, 1- (4-methoxyphenyl)-, dihydrochloride
Target:
Research Areas:
1-(4-Methoxyphenyl)piperazine (Piperazine, 1- (4-methoxyphenyl)-) hydrochloride is a piperazine derivative with neural activity .
Cat. No.: HY-W145436
CAS No.: 2222114-23-8
Research Areas:
Thalidomide-Piperazine 5-fluoride hydrochloride is a derivative of cereblon (CRBN) inhibitor Thalidomide (HY-14658), which can be used as ligands for E3 ubiquitin ligase (Ligands for E3 Ligase) for PROTACs Synthesis .
Research Areas:
Pipobroman is a bromide derivative of piperazine and acts as an alkylating agent. Pipobroman plays its role by inhibiting DNA and RNA polymerase or by reducing pyrimidine nucleotide incorporation into DNA. Pipobroman can be used for the cancer research, including polycythemia vera, myeloproliferative neoplasm, and AML et.al .
Cat. No.: HY-40041
CAS No.: 163765-44-4
Cat. No.: HY-40040
CAS No.: 147081-29-6
Cat. No.: HY-B1505A
CAS No.: 18833-13-1
Synonyms: Theophyllineacetic acid piperazine; Theophylline-7-acetic acid piperazine
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Acefylline (Theophyllineacetic acid) piperazine, a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline piperazine is a peptidylarginine deiminase (PAD) activator. Acefylline piperazine is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline piperazine can be used in asthma research .
Cat. No.: HY-66010
CAS No.: 26328-04-1
Synonyms: MD-67350
Target:
Research Areas:
Cinepazide Maleate (MD-67350) is a piperazine derivative and acts as a weak calcium channel blocker. Cinepazide Maleate is a potent vasodilator and can be used for the research of cerebrovascular diseases, including ischemic stroke, brain?infarct et. al .
Cat. No.: HY-123207
CAS No.: 82900-57-0
Target:
Research Areas:
BP 554 is a selective 5-HT1A receptor agonist and Piperazine derivative. BP 554 leads to hypothermia .
Target:
Research Areas:
Cyclizine lactate, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine lactate can be used for the research of nausea, vomiting, and dizziness .
Cat. No.: HY-20128S
CAS No.: 1219803-71-0
Target:
Research Areas:
Cyclizine hydrochloride, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine hydrochloride can be used for the research of nausea, vomiting, and dizziness .
Cat. No.: HY-137162
CAS No.: 84625-59-2
Research Areas:
Dotarizine is a novel Piperazine (HY-B0912) derivative and antimigraine agent. Dotarizine exhibits Ca 2+ channel blocking properties. Dotarizine decreases the release of lactate dehydrogenase. Dotarizine shows 5-HT receptor blocking effect .
Cat. No.: HY-177282
CAS No.: 524743-70-2
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
SST1 receptor antagonist-2 (Example 2) is a piperazine derivative and a somatostatin receptor 1 (SST1) antagonist. SST1 receptor antagonist-2 can be used in the research of psychiatric diseases, neurodegenerative diseases, tumors, as well as vascular disorders and immunological diseases .
Cat. No.: HY-165555
CAS No.: 904576-65-4
MMV665917 is an orally active piperazine derivative with anti-Cryptosporidium parvum activity with an EC90 of 15 μM. MMV665917 significantly reduces the parasite load in a porcine model infected with C. hominis, decreases ovarian excretion, alleviates diarrhea symptoms and reduces intestinal mucosal damage. MMV665917 can be used for research on Cryptosporidium parvum disease .
Target:
Research Areas:
TVD-0003510 is a carboxamide derivative, and involves in synthesis of (2-((6-(2-aminopyrimidine-5-carboxamido)-8-methoxy-3,4-dihydro-2H-pyrimido[1,2-c]quinazolin-9-yl)oxy)ethyl)piperazine-l-carboxylate (C51), as a part of tert-butyl2-(4-hydroxyphenyl)acetate .
Cat. No.: HY-W013376
CAS No.: 841-77-0
Synonyms: 1-(Diphenylmethyl)piperazine; 1-Benzhydrylpiperazine
Norcyclizine is a piperazine compound that can be used for the synthesis of antimicrobial agents. 1-Benzhydrylpiperazine derivatives have been found to enhance the antibacterial activity of β-lactam antibiotics (Oxacillin, HY-B0925A) against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA). This enhancement is likely achieved by inhibiting the allosteric site of PBP2a. Additionally, 1-Benzhydrylpiperazine can also serve as a pharmacological scaffold for the synthesis of anticancer agents .
Target:
Research Areas:
Piposulfan (Ancyte) is a methanesulfonate, alkylating derivative of piperazine. Piposulfan has potential antineoplastic activity. Piposulfan can be used for the research of cancer .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
