5897-19-8
5897-19-8
Chemical Structure
Cyclizine lactate
- CAS No.: 5897-19-8
- Formula:C21H28N2O3
- Molecular Weight:356.46
IUPAC Name: 1-benzhydryl-4-methylpiperazine 2-hydroxypropanoate
InChIKey: JOROEVAWQLGPFQ-UHFFFAOYSA-N
SMILES: CN1CCN(C(C2=CC=CC=C2)C3=CC=CC=C3)CC1.OC(C)C(O)=O
Biological Activity: Cyclizine lactate, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine lactate can be used for the research of nausea, vomiting, and dizziness[1][2][3].
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Cyclizine lactate | Cyclizine lactate, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine lactate can be used for the research of nausea, vomiting, and dizziness. | |||||||||||||||||||||
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References
- [1]. Králová J, et, al. The effects of H1-antihistamines on the nitric oxide production by RAW 264.7 cells with respect to their lipophilicity. Int Immunopharmacol. 2009 Jul;9(7-8):990-5. [Content Brief]
- [2]. Church MK, et, al. Inhibition of histamine release from human lung in vitro by antihistamines and related drugs. Br J Pharmacol. 1980 Aug;69(4):663-7. [Content Brief]
- [3]. Leza JC, et, al. Effects of antihistaminics on locomotor activity in mice. Comparison with opiate and amphetamine-induced hyperactivity. Gen Pharmacol. 1991;22(2):293-6. [Content Brief]
