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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
prostacyclin analog
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "prostacyclin analog" in MCE Product Catalog:
Synonyms: TRK-100; ML 1129 sodium
Target:
Research Areas:
Beraprost sodium (TRK-100), a prostacyclin analog, is a stable and orally active proagent of PGI2. Beraprost sodium (TRK-100) is a potent vasodilator, has the potential for pulmonary arterial hypertension treatment through expanding renal vessels, improving microcirculation . Beraprost sodium (TRK-100) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-127162
CAS No.: 69413-73-6
Synonyms: PGK1
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Prostaglandin K1 (compound 46) is a structurally modified analog of prostacyclin (prostanoid) with an EC50 of 2800 nM for EP1 and a Ki of 2800 nM .
Cat. No.: HY-13569AR
CAS No.: 496807-11-5
Synonyms: TRK-100 (Standard); ML 1129 sodium (Standard)
Research Areas:
Beraprost (sodium) (Standard) is the analytical standard of Beraprost (sodium). This product is intended for research and analytical applications. Beraprost sodium, a prostacyclin analog, is a stable and orally active proagent of PGI2. Beraprost sodium is a potent vasodilator, has the potential for pulmonary arterial hypertension treatment through expanding renal vessels, improving microcirculation . Beraprost (sodium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-106110
CAS No.: 101758-79-6
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OP-2507 is a prostacyclin analog. OP-2507 can increase brain glucose levels in mice, suppress the breakdown of energy metabolism under hypoxic conditions, and has a protective effect against changes in cyclic nucleotides in hypoxic brain tissue (specifically, an increase in cyclic AMP and a decrease in cyclic GMP). OP-2507 provides protective effects against brain hypoxia and edema .
Cat. No.: HY-160993
CAS No.: 81845-44-5
Synonyms: 9β-Methylcarbacyclin
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Ciprostene is analog of prostacyclin (PGI2). Ciprostene inhibits adenosine diphosphate-induced platelet aggregation. Ciprostene can be used for research of peripheral vascular disease .
Cat. No.: HY-167091
CAS No.: 88430-50-6
Synonyms: (Rac)-TRK-100 free acid; (Rac)-ML 1229
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(Rac)-Beraprost ((Rac)-ML 1229) is an orally active prostacyclin analog that inhibits the release of Ca 2+ from intracellular storage sites by binding to prostacyclin membrane receptors (Prostaglandin Receptor), leading to relaxation of smooth muscle cells and vasodilation. Beraprost has vasodilatory, antiplatelet, and cytoprotective effects, making it promising for research in the field of cardiovascular diseases, such as thromboangiitis obliterans and atherosclerosis .
Cat. No.: HY-Z7721
CAS No.: 88475-69-8
Synonyms: (Rac)-TRK-100; (Rac)-ML 1129 sodium
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Research Areas:
(Rac)-Beraprost ((Rac)-ML 1129) sodium is a racemic isomer of Beraprost sodium (HY-13569A). Beraprost sodium is an orally active prostacyclin analog that inhibits the release of Ca 2+ from intracellular storage sites by binding to prostacyclin membrane receptors (Prostaglandin Receptor), leading to relaxation of smooth muscle cells and vasodilation. Beraprost sodium has vasodilatory, antiplatelet, and cytoprotective effects, making it promising for research in the field of cardiovascular diseases, such as thromboangiitis obliterans and atherosclerosis .
Cat. No.: HY-137227
CAS No.: 71154-83-1
Synonyms: 15(R)-Pinanethromboxane A2
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15(R)-PTA2 (15(R)-Pinanethromboxane A2) is an antithrombotic agent that inhibits platelet aggregation. 15(R)-PTA2 inhibits stable prostaglandin endoperoxide analog-induced constriction of feline coronary arteries and stabilizes hepatic lysosomes. 15(R)-PTA2 also inhibits thromboxane synthase but has no effect on prostacyclin synthase .
Cat. No.: HY-106099
CAS No.: 95722-07-9
Synonyms: (R)-ZK 96480
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Research Areas:
(R)-Cicaprost ((R)-ZK 96480) is an isomer of Cicaprost (HY-19583). Cicaprost is an orally active prostacyclin analog. Cicaprost inhibits platelet aggregation and release, and induces vasodilation. Cicaprost can be used in research related to breast cancer and pulmonary arterial hypertension .
Cat. No.: HY-187559
CAS No.: 99570-57-7
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U 68215 is an orally active benzindene prostacyclin (PGI2) analog. U 68215 exhibits potent anti-gastric ulcer and gastric emptying inhibitory effects without inducing side effects such as diarrhea. U 68215 can be used in studies on peptic ulcer treatment and gastrointestinal cytoprotection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
