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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
reserpinized rats
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "reserpinized rats" in MCE Product Catalog:
Cat. No.: HY-180422
CAS No.: 95999-11-4
Target:
Research Areas:
(-)-UH 232 is a central dopamine (DA) receptor agonist. (-)-UH 232 weakly decreases 3, 4-dihydroxyphenylalanine (DOPA) formation in striatal and limbic brain regions in rats. (-)-UH 232 can be used for the research of neurological diseases including parkinson's disease and schizophrenia .
Research Areas:
NSD 1034 is a potent inhibitor of aromatic L-amino acid decarboxylase (AADC) and tyrosine aminotransferase (TAT), with IC50 values of 0.32 μM and 80 μM, respectively. NSD 1034 increases dopamine synthesis and release by inhibiting AADC and TAT, and stimulating tyrosine hydroxylase in dopaminergic neurons via calcium influx in a classical dopamine receptor-independent manner. NSD 1034 is used in studies of Parkinson's disease and sleep disorders .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
