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Pathways Recommended: Stem Cell/Wnt
Results for "

stem extracts

" in MedChemExpress (MCE) Product Catalog:

30

Inhibitors & Agonists

1

MCE Kits

26

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1581
    Quassin

    Nigakilactone D

    		 Parasite Infection Endocrinology
    Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity .
    Quassin
  • HY-N13250
    Hawthorn Extract

    		Apoptosis AMPK Elastase Bcl-2 Family Interleukin Related Caspase PI3K Akt SOD Cardiovascular Disease
    Hawthorn Extract is an orally active hawthorn extract. Hawthorn Extract decreases Bax expression and increases Bcl-2 expression in the aorta. Hawthorn Extract regulates the AMPK signaling pathway, induces apoptosis, enhances the hepatic antioxidant system, and ameliorates symptoms of liver injury, inflammation and cancer. Hawthorn Extract reduces plasma levels of pro-inflammatory factors, increases plasma levels of anti-inflammatory adiponectin, and alleviates atherosclerotic plaque lesions in the aorta. Hawthorn Extract improves symptoms associated with chronic heart failure . Hawthorn Extract inhibits FMLP-induced superoxide anion production, Elastase release, ILB4 generation and calcium signaling in neutrophils, and also reduces LPS-induced cytokine production in neutrophils. Hawthorn Extract induces autophagy and inhibits the proliferation of intestinal stem cells. Hawthorn Extract can be used in research related to atherosclerosis, hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, hepatocellular carcinoma, chronic heart failure and hypotension .
    Hawthorn Extract
  • HY-N2732
    6-Prenylapigenin

    6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin

    		 Others Cancer
    6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells .
    6-Prenylapigenin
  • HY-N0975
    1,11b-Dihydro-11b-hydroxymaackiain

    		Others Metabolic Disease
    1,11b-Dihydro-11b-hydroxymaackiain, a pterocarpane extract from the stems of Erycibe expansa, show a hepatoprotective effect .
    1,11b-Dihydro-11b-hydroxymaackiain
  • HY-N3706
    Dehydro-α-lapachone

    		Fungal Infection
    Dehydro-α-lapachone can be isolated from the methanol extract of stems of Catalpa ovata G Don. Dehydro-α-lapachone inhibits mycelial growth of Botrytis cinerea with IC50 value 0.41 mg/L .
    Dehydro-α-lapachone
  • HY-N3642
    Cristacarpin

    Erythrabyssin I; Erythrabissin I

    		 Others Cancer
    Cristacarpin can be extracted from the stem bark of Erythrina suberosa, promotes endoplasmic reticulum (ER) stress, leading to sublethal reactive oxygen species (ROS) production and ultimately cell death through senescence .
    Cristacarpin
  • HY-N1251
    Scholaricine

    		Others Others
    Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM .
    Scholaricine
  • HY-145686
    AV023

    		Wnt Nuclear Factor of activated T Cells (NFAT) Inflammation/Immunology
    AV023 is a potent inhibitor of ANKRD22. AV023 promotes the expansion of gastrointestinal mucosal epithelial stem cells and indirectly activates the Wnt classical pathway, which helps the recovery of damaged gastrointestinal mucosal tissues in the body (extracted from patent CN111205231B) .
    AV023
  • HY-N3554
    Catechin-7-O-β-D-xylopyranoside

    (+)-Catechol 7-β-D-xylopyranoside

    		 Others Others
    Catechin-7-O-β-D-xylopyranoside is an antioxidant compound with strong DPPH free radical scavenging ability. Catechin-7-O-β-D-xylopyranoside can be extracted from birch inner bark and nepeta stem bark .
    Catechin-7-O-β-D-xylopyranoside
  • HY-N1014
    11α,12β-Di-O-acetyltenacigenin B

    		Others Others
    11α,12β-Di-O-acetyltenacigenin B is a polyoxypregnane compound isolated from the CHCl(3)-soluble fraction of the ethanolic extract of the stem of Marsdenia tenacissima .
    11α,12β-Di-O-acetyltenacigenin B
  • HY-N3597
    Clerodenoside A

    Diacetylmartynoside

    		 Others Others
    Clerodenoside A is a phenolic glycoside that can be extracted from the stem of Clerodendrum inerme .
    Clerodenoside A
  • HY-117034
    Rankinidine

    		Others Others
    Rankinidine is an oxindole alkaloid that is isolated from the MeOH extract of the stem of Gelsemium rankinii .
    Rankinidine
  • HY-N3374
    Lochnerine

    10-O-Methylsarpagine

    		 Others Others
    Lochnerine is an indole alkaloid can be isolated from the stem bark extract of Alstonia macrophylla .
    Lochnerine
  • HY-N1019
    11-Hydroxyhumantenine

    N-Methyl-11-hydroxyrankinidine

    		 Others Others
    11-Hydroxyhumantenine is an alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .
    11-Hydroxyhumantenine
  • HY-N12439
    2,2′-Dihydroxy-4,6-dimethoxy-3-methylacetophenone

    		Others Others
    2,2′-Dihydroxy-4,6-dimethoxy-3-methylacetophenone can be isolated from the EtOAc extract of spurge stems.
    2,2′-Dihydroxy-4,6-dimethoxy-3-methylacetophenone
  • HY-N1018
    11-Hydroxygelsenicine

    		Others Others
    11-Hydroxygelsenicine is a 11-hydroxy-substituted gelsedine-type indole alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .
    11-Hydroxygelsenicine
  • HY-N7324
    Dehydroperilloxin

    		COX Inflammation/Immunology
    Dehydroperilloxin is a natural compound isolated from the dichloromethane extract of the stems of Perilla frutescens var. acuta. Dehydroperilloxin possesses inhibitory activity against cyclooxygenase-1, with the IC50 value of 30.4 μM .
    Dehydroperilloxin
  • HY-N11970
    Isocrenatoside

    		Angiotensin-converting Enzyme (ACE) Metabolic Disease
    Isocrenatoside (compound 6) is a cyclic octapeptide and an inhibitor of angiotensin-converting enzyme (ACE). Isocrenatoside is isolated from the ethanolic extract of Microtoena prainiana stems. Studies have found that the inhibitory efficiency of 1 mg/mL Isocrenatoside can reach 99.3% .
    Isocrenatoside
  • HY-N1581R
    Quassin (Standard)

    Nigakilactone D (Standard)

    		 Reference Standards Parasite Infection Endocrinology
    Quassin (Standard) is the analytical standard of Quassin. This product is intended for research and analytical applications. Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity .
    Quassin (Standard)
  • HY-N9790
    Procyanidin B2 3,3'-di-O-gallate

    		Notch Others
    Procyanidin B2, 3,3'-di-O-gallate is an active constituent. Procyanidin B2, 3,3'-di-O-gallate can be isolated from grape seed extract (GSE) procyanidin mix. Procyanidin B2, 3,3' -di-o-gallate target cancer stem cells (CSCs) in prostate cancer (PCa). Procyanidin B2, 3,3'-di-O-gallate targets both unsorted and sorted CSCs at lower doses. Procyanidin B2, 3,3'-di-O-gallate strongly suppresses the constitutive as well as Jagged1 (Notch1 ligand)-induced activated Notch1 pathway .
    Procyanidin B2 3,3'-di-O-gallate
  • HY-N19776
    7-O-Methylherbacetin 3-rhamnoside

    		Others Others
    7-O-Methylherbacetin 3-rhamnoside (Compound 42) is a flavonoid compound. 7-O-Methylherbacetin 3-rhamnoside can be isolated from Atraphaxis pyrifolia .
    7-O-Methylherbacetin 3-rhamnoside
  • HY-N16768
    Alangilignoside B

    		Others Others
    Alangilignoside B is a benzofuran-type neolignan glycoside compound that can be naturally extracted from the stems of Alangium premnifolium .
    Alangilignoside B
  • HY-N16875
    Cincholic acid 3-O-β-D-quinovopyranoside

    		Drug Derivative Others
    Cincholic acid 3-O-β-D-quinovopyranoside is a natural triterpene.
    Cincholic acid 3-O-β-D-quinovopyranoside
  • HY-N16759
    Apparicine

    		Others Cancer
    Apparicine is a monoterpene indole alkaloid that can be naturally extracted from the stems of Tabernaemontana divaricata. Apparicine shows no cytotoxicity against MCF-7 human breast cancer cells and A-549 human lung cancer cells .
    Apparicine
  • HY-N9833
    Sampsone B

    		Bacterial Infection
    Sampsone B is a dihydrodibenzodioxinone-type antibacterial agent with a minimum inhibitory concentration (MIC) of ≥128 μg/mL against methicillin-resistant Staphylococcus aureus (MRSA). Sampsone B can be naturally extracted from the aerial parts (stems and leaves) of Hypericum sampsonii .
    Sampsone B
  • HY-N9835
    Thymol isobutyrate

    		Drug Derivative Infection Cancer
    Thymol isobutyrate is a thymol derivative that can be naturally extracted from the essential oil of the roots and aerial parts (leaves, stems, and flowers) of Carpesium cernuum L. This plant's essential oil has antibacterial and cytotoxic activity and can be used in antibacterial and antitumor research .
    Thymol isobutyrate
  • HY-N9707
    15-Nonacosanol

    		Others Others
    15-Nonacosanol is a secondary alcohol compound and the major surface lipid component of Arabidopsis thaliana cuticular wax. 15-Nonacosanol participates in the plant cuticular wax biosynthesis pathway and the formation process of related gene mutants. 15-Nonacosanol can be extracted from the leaves and stems of Arabidopsis thaliana .
    15-Nonacosanol
  • HY-N18670
    Panax notoginseng extract

    		Others Others
    Panax notoginseng extract is derived from the stems and leaves of Panax notoginseng, a plant belonging to the Araliaceae family. Its main active ingredient is notoginsenoside (PNS), among which notoginsenoside Rb1, notoginsenoside Rg1, and notoginsenoside R1 are present in high amounts and can be used for skin conditioning in functional cosmetics.
    Panax notoginseng extract
  • HY-N16714
    Clausine K

    		Others Cancer
    Clausine K is a carbazole alkaloid anticancer agent. Clausine K exhibits strong cytotoxicity against human hepatoma HepG2 cells (IC50 = 1.05 μg/mL), superior to the standard drug Etoposide (HY-13629) (IC50 13.40 μg/mL). Clausine K can be naturally extracted from the dried stems of Clausena excavata (a plant of the Rutaceae family) through chromatographic separation and other methods .
    Clausine K
  • HY-N16764
    (rel)-Salcolin A

    		Necroptosis NO Synthase Neurological Disease Inflammation/Immunology Endocrinology Cancer
    (rel)-Salcolin A is a flavonoid lignan compound with anticancer, anti-inflammatory, and neuroprotective activities. (rel)-Salcolin A has IC50 values ??of 66.69 μM and 56.12 μM against anaplastic thyroid carcinoma cells (HTH83) and papillary thyroid carcinoma cells (TPC1), respectively. (rel)-Salcolin A also inhibits LPS-induced NO production with an IC50 of 14.65 μM. (rel)-Salcolin A exerts its effects by inducing necroptosis in thyroid cancer cells, inhibiting the production of the inflammatory factor NO, and protecting against glutamate-induced neuronal cell damage, with a neuroprotective E50 of 47.44 μM. (rel)-Salcolin A can be used in research related to thyroid cancer, anti-inflammation, and neuroprotection. (rel)-Salcolin A can be naturally extracted from the leaves of Casearia arborea and the stems of Zea mays (corn) .
    (rel)-Salcolin A

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