Cristacarpin
Cristacarpin can be extracted from the stem bark of Erythrina suberosa, promotes endoplasmic reticulum (ER) stress, leading to sublethal reactive oxygen species (ROS) production and ultimately cell death through senescence.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 74515-47-2
- 화학식: C21H22O5
- 분자량:354.40
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
3.36 μM
Compound: 8
|
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 28189086] |
| CHO | IC50 |
>20 μM
Compound: 2
|
Cytotoxicity against CHO cells
Cytotoxicity against CHO cells
|
[PMID: 8277323] |
| CHO | IC50 |
4 μM
Compound: 2
|
Cytotoxicity against p-glycoprotein overexpressing CHO cells
Cytotoxicity against p-glycoprotein overexpressing CHO cells
|
[PMID: 8277323] |
| P388 | IC50 |
>10 μM
Compound: 2
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 8277323] |
Chemical Information
-
CAS No. 74515-47-2
-
분자량 354.40
-
화학식 C21H22O5
-
SMILES
O[C@]12[C@](OC3=C(C/C=C(C)\C)C(OC)=CC=C32)([H])C4=CC=C(O)C=C4OC1
-
Synonyms
Erythrabyssin I; Erythrabissin I
-
Initial Source
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)