99694-90-3
Chemical Structure
Scholaricine
- CAS No.: 99694-90-3
- Formula:C20H24N2O4
- Molecular Weight:356.42
IUPAC Name: (3aS,5S,11bR,12S)-methyl 8-hydroxy-12-((S)-1-hydroxyethyl)-1,2,3a,4,5,7-hexahydro-5,3-ethanopyrrolo[2,3-d]carbazole-6-carboxylate
InChIKey: GNCUCBQZLQLSOF-IGWMUPSQSA-N
SMILES: COC(C1=C2[C@]3(C4=CC=CC(O)=C4N2)[C@@]5([H])N(C[C@]([C@]1([H])C5)([H])[C@@H](O)C)CC3)=O
Biological Activity: Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM[1].
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Scholaricine | Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC50 value of 13.35 μM. | |||||||||||||||||||||
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Keywords
