133 Results for "

stomach

" in MedChemExpress (MCE) Product Catalog:
Products (133)

133 Results for "stomach" in MCE Product Catalog:

23
23 Publications Verification
Cat. No.: HY-N0171
CAS No.: 83-46-5
Beta-Sitosterol (purity≥80%) is orally active. Beta-Sitosterol exhibits multiple activities, including anti-inflammatory, anticancer, antioxidant, antimicrobial, antidiabetic, antioxidant enzyme, and analgesic. Beta-Sitosterol inhibits inflammation and impaired adipogenesis in bovine mammary epithelial cells by reducing levels of ROS, TNF-α, IL-1β, and NF-κB p65 and restoring the activity of the HIF-1α/mTOR signaling pathway. Beta-Sitosterol induces apoptosis in cancer cells through ROS-mediated mitochondrial dysregulation and p53 activation. Beta-Sitosterol exerts its anticancer effects in cancer cells by activating caspase-3, caspase-8, and caspase-9, mediating PARP inactivation, MMP loss, altered Bcl-2-Bax ratio, and cytochrome c release. Beta-Sitosterol modulates macrophage polarization and reduces rheumatoid inflammation in mice. Beta-Sitosterol inhibits tumor growth in multiple mouse cancer models. Beta-Sitosterol can be used in the research of arthritis, lung cancer, breast cancer and other cancers, diabetes, etc .
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17
17 Cited Publications
Cat. No.: HY-P1097
CAS No.: 10047-33-3
Research Areas:  

Endocrinology

Gastrin I, human is the endogenous peptide produced in the stomach, and increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor.
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12
12 Cited Publications
Cat. No.: HY-13625
CAS No.: 153773-82-1
Synonyms: L-749345; MK-826
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Cancer

Ertapenem sodium (L-749345) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
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12
12 Cited Publications
Cat. No.: HY-A0294A
CAS No.: 153832-38-3
Synonyms: MK-0826 disodium
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Cancer

Ertapenem (MK-0826) disodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
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12
12 Cited Publications
Cat. No.: HY-P7014
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF4; Heparin-Binding Growth Factor 4; Prev. HSTF1; HSTF-1; HBGF-4; FGF-4; HST-1; Heparin Secretory-Transforming Protein 1; HST; Fibroblast Growth Factor; Transforming Protein KS3; Oncogene HST; K-FGF; SRTD22; KFGF; KS3; Human stomach Cancer, Transforming
Species:  
Source:  
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6
6 Cited Publications
Cat. No.: HY-B0411
CAS No.: 57808-66-9
Synonyms: R33812
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Domperidone (R33812) is an orally active and selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine .
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6
6 Cited Publications
Cat. No.: HY-B0411A
CAS No.: 83898-65-1
Synonyms: R33812 monomaleate
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Domperidone (R33812) monomaleate is an orally active and selective dopamine-2 receptor antagonist. Domperidone monomaleate acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine .
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5
5 Cited Publications
Cat. No.: HY-13662
CAS No.: 103577-45-3
Purity:  99.83%
Synonyms: AG-1749
Lansoprazole (AG 1749) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) .
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5
5 Cited Publications
Cat. No.: HY-13662A
CAS No.: 226904-00-3
Synonyms: AG-1749 sodium
Lansoprazole sodium (AG 1749 sodium) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole sodium (AG 1749 sodium) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) .
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3
3 Cited Publications
Cat. No.: HY-P1635
CAS No.: 9001-75-6
Synonyms: EC 3.4.23.1
Target:  

Endogenous Metabolite

Research Areas:  

Endocrinology

Pepsin is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin contributes to proteolysis of food proteins in the vertebrate stomach .
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3
3 Cited Publications
Cat. No.: HY-12204
CAS No.: 4382-63-2
Purity:  99.80%
Target:  

Autophagy

PFK-015, a derivative of 3PO, is a specific PFKFB3 inhibitor. PFK-015 inhibits recombinant PFKFB3 with an IC50 value of 110 nM and inhibits PFKFB3 activity in cancer cells with an IC50 value of 20 nM. PFK-015 can be used for the research of multiple cancers such as lung cancer, stomach cancer, colon cancer and esophageal squamous cell carcinoma (ESCC) .
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3
3 Cited Publications
Cat. No.: HY-E70198
CAS No.: 9001-75-6
Synonyms: EC 3.4.23.1 (MS Grade)
Target:  

Endogenous Metabolite

Research Areas:  

Others

Pepsin (MS Grade) is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin (MS Grade) contributes to proteolysis of food proteins in the vertebrate stomach .
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2
2 Cited Publications
Cat. No.: HY-13662B
CAS No.: 138530-94-6
Purity:  98.91%
Synonyms: Dexlansoprazole
Target:  

Exosomes Proton Pump

Research Areas:  

Inflammation/Immunology Cancer

(R)-Lansoprazole is the R enantiomer of Lansoprazole, Lansoprazole (AG 1749) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) .
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2
2 Cited Publications
Cat. No.: HY-N0925
CAS No.: 522-97-4
Synonyms: Canadine
Tetrahydroberberine is a different kind of living thing that can be extended and divided into parts. Tetrahydroberberine is a kind of effective D2 receptor antagonistic force. Tetrahydroberberine has the ability to strengthen the stomach and relieve the pressure on the stomach .
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2
2 Cited Publications
Cat. No.: HY-N0671
CAS No.: 155-58-8
Synonyms: Rhaponiticin
Rhapontin (Rhaponiticin) is an orally aactive SIRT1 agonist and AMPK activator with anti-inflammatory and anti-fibrotic activities. Rhapontin inhibits NLRP3 inflammasome activation by activating SIRT1 and inhibits TGF-β/Smad signaling via the AMPK pathway. Rhapontin reduces intestinal and lung inflammation, inhibits fibroblast differentiation and extracellular matrix deposition, and enhances tight junction protein expression to repair epithelial barriers. Rhapontin can be used in the study of inflammatory bowel diseases (such as ulcerative colitis) and pulmonary fibrosis .
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2
2 Cited Publications
Cat. No.: HY-B0310
CAS No.: 76963-41-2
Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models .
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2
2 Cited Publications
Cat. No.: HY-106840
CAS No.: 118101-09-0
Purity:  99.93%
L-365260 is an orally active and selective antagonist of non-peptide gastrin and brain cholecystokinin receptor (CCK-B), with Kis of 1.9 nM and 2.0 nM, respectively. L-365260 interacts in a stereoselective and competitive manner with guinea pig stomach gastrin and brain CCK receptors. L-365260 can enhance Morphine analgesia and prevents Morphine tolerance .
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2
2 Cited Publications
Cat. No.: HY-106840A
Purity:  99.75%
L-365260 hemihydrate is an orally active and selective antagonist of non-peptide gastrin and brain cholecystokinin receptor (CCK-B), with Kis of 1.9 nM and 2.0 nM, respectively. L-365260 hemihydrate interacts in a stereoselective and competitive manner with guinea pig stomach gastrin and brain CCK receptors .
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2
2 Cited Publications
Cat. No.: HY-B0900
CAS No.: 104-46-1
Synonyms: Anise camphor; p-Propenylanisole; Isoestragole
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .
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2
2 Cited Publications
Cat. No.: HY-12017
CAS No.: 956905-27-4
Purity:  99.85%
PF-04217903 is an orally active, highly selective ATP-competitive c-Met kinase inhibitor with a Ki value of 4.8 nM and a Kd value of 4.5 nM. PF-04217903 blocks c-Met and HGF signaling pathways, inhibits MET phosphorylation, and blocks downstream MAPK, PI3K/AKT and PLCγ1 pathways. PF-04217903 suppresses tumor proliferation, survival, migration, invasion, angiogenesis and metastasis, induces apoptosis, and enhances efferocytosis, Annexin A1 expression and resolution of inflammation. PF-04217903 retains activity against several c-Met mutants (M1131T, V1220I, H1094R). PF-04217903 increases the incidence of subarachnoid hemorrhage and reduces survival rate without altering aneurysm formation, and also prevents lymph node metastasis induced by VEGF inhibition. PF-04217903 is applicable to research related to tumors (pancreas, stomach, lung, brain, colon, breast, kidney, melanoma, etc.), intracranial aneurysms and inflammatory diseases (gouty arthritis, neutrophilic pleuritis) .
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