2. Cytoskeleton Membrane Transporter/Ion Channel Metabolic Enzyme/Protease Anti-infection
  3. Exosomes Proton Pump Phospholipase Bacterial
  4. Lansoprazole sodium

Lansoprazole sodium  (Synonyms: AG-1749 sodium)

Cat. No.: HY-13662A Purity: 98.80%
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Lansoprazole sodium (AG 1749 sodium) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole sodium (AG 1749 sodium) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).

For research use only. We do not sell to patients.

CAS No. : 226904-00-3

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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10 mM * 1 mL in DMSO In-stock
Solid
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50 mg In-stock
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Customer Review

Based on 3 publication(s) in Google Scholar

Other Forms of Lansoprazole sodium:

Lansoprazole sodium Related Antibodies

Top Publications Citing Use of Products
Bio/Physico-chemical Assay

    Lansoprazole sodium purchased from MedChemExpress. Usage Cited in: Results Chem. 2024 Oct.

    Zero-order absorption spectra of 5.0 µg/mL (LEV, RAB, LAN (Lansoprazole), PAR, and AMO).

    Lansoprazole sodium purchased from MedChemExpress. Usage Cited in: Results Chem. 2024 Oct.

    Determination of LEV, RAB, Lansoprazole (LAN), PAR, and AMO in the pharmaceutical formulation by chemometric techniques and application of the standard addition technique.

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    Description

    Lansoprazole sodium (AG 1749 sodium) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole sodium (AG 1749 sodium) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)[1][2].

    Clinical Trial
    Molecular Weight

    391.34

    Formula

    C16H13F3N3NaO2S
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O=S(C1=NC2=CC=CC=C2[N-]1)CC3=NC=CC(OCC(F)(F)F)=C3C.[Na+]
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 6 months
    -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : 125 mg/mL (319.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.5553 mL 12.7766 mL 25.5532 mL
    5 mM 0.5111 mL 2.5553 mL 5.1106 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

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    Calculation results:
    Working solution concentration: mg/mL
    Purity & Documentation
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO 1 mM 2.5553 mL 12.7766 mL 25.5532 mL 63.8831 mL
    5 mM 0.5111 mL 2.5553 mL 5.1106 mL 12.7766 mL
    10 mM 0.2555 mL 1.2777 mL 2.5553 mL 6.3883 mL
    15 mM 0.1704 mL 0.8518 mL 1.7035 mL 4.2589 mL
    20 mM 0.1278 mL 0.6388 mL 1.2777 mL 3.1942 mL
    25 mM 0.1022 mL 0.5111 mL 1.0221 mL 2.5553 mL
    30 mM 0.0852 mL 0.4259 mL 0.8518 mL 2.1294 mL
    40 mM 0.0639 mL 0.3194 mL 0.6388 mL 1.5971 mL
    50 mM 0.0511 mL 0.2555 mL 0.5111 mL 1.2777 mL
    60 mM 0.0426 mL 0.2129 mL 0.4259 mL 1.0647 mL
    80 mM 0.0319 mL 0.1597 mL 0.3194 mL 0.7985 mL
    100 mM 0.0256 mL 0.1278 mL 0.2555 mL 0.6388 mL
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    Lansoprazole sodium Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Lansoprazole226904-00-3AG-1749AG1749AG 1749ExosomesProton PumpPhospholipaseBacterialInhibitorinhibitorinhibit

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