2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Pepsin

Pepsin is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin contributes to proteolysis of food proteins in the vertebrate stomach.

For research use only. We do not sell to patients.

Pepsin

Pepsin Chemical Structure

CAS No. : 9001-75-6

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Based on 3 publication(s) in Google Scholar

Other Forms of Pepsin:

Pepsin Related Antibodies

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Human Endogenous Metabolite Microbial Metabolite

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Description

Pepsin is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin contributes to proteolysis of food proteins in the vertebrate stomach[1][2].

In Vitro

Optimal pH: 1.0-3.0.
Activators: Hydrochloric acid (HCl), trifluoroacetic acid (TFA).
Inactivators: pH greater than 6.0.
Usage Notes:
1. Resuspend Pepsin in double-distilled water (pH 5.5 or lower) to a final concentration of 1mg/mL. Store reconstituted Pepsin at 4 °C for up to 1 month.
2. Specificity for cleavage at Phe and Leu is best at pH 1.0 and decreased above pH 2.0. Pepsin irreversibly inactivates above pH 6.0.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Pepsin Related Antibodies
Clinical Trial
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

[Pepsin]
EC Number

3.4.23.1
Enzyme Activity

>3000 U/mg soild
Unit Definition

One unit is defined as the amount of enzyme that catalyzes the hydrolysis of hemoglobin to produce 1 μmol of tyrosine per minute at 37℃, pH 2.

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

0.01 M HCl : ≥ 2 mg/mL

*"≥" means soluble, but saturation unknown.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

SDS (558 KB)

COA (242 KB)

Handling Instructions (2659 KB)
References
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Pepsin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pepsin9001-75-6EC 3.4.23.1Endogenous Metabolitegastric proteasegastric proteolytic enzymeproteolysisstomachInhibitorinhibitorinhibit

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