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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
140 Results for "
thiol-groups
" in MedChemExpress (MCE) Product Catalog:
Products (140)
140 Results for "thiol-groups" in MCE Product Catalog:
15
3
3 Cited Publications
Target:
Research Areas:
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
2
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2
2 Cited Publications
Cat. No.: HY-166648A
DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
2
2 Cited Publications
Cat. No.: HY-166648
DSPE-PEG2000-Maleimide sodium (purity>98%) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG2000-Maleimide sodium (purity>98%) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG2000-RGD. DSPE-PEG2000-Maleimide sodium (purity>98%) is applicable to research on drug delivery .
1
1 Cited Publications
Synonyms: Cyanine5 maleimide
1
1
Research Areas:
Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections .
1
1 Cited Publications
Cat. No.: HY-D1423
CAS No.: 68654-25-1
Target:
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Dibromobimane is a Fluorescent dye and probe that can be used for the detection of intracellular reduced glutathione and the analysis of spatial proximity of closely adjacent cysteine thiol groups. Dibromobimane activates fluorescence through binding to thiol groups; its excitation/emission wavelengths are Ex/Em = 393/477 nm for glutathione detection, and Ex/Em = 385/477 nm for cysteine thiol cross-linking. Dibromobimane uses two equivalent bromomethyl groups to cross-link cysteine thiolates with a distance ranging from 3-6 Å. Dibromobimane can be applied to 96-well microplate-based high-throughput assays for labeling intracellular glutathione, and its fluorescence signal is normalized against nuclear staining results to eliminate the impact of cell density .
Cat. No.: HY-W068119A
CAS No.: 134272-64-3
Synonyms: 2-Maleimidoethylamine hydrochloride
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Biotin-BMCC is a Maliemide (HY-W007324) conjugated biotin molecule that has a high affinity for free thiol groups of cysteines .
Cat. No.: HY-140651
Purity: ≥93.0%
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Amine-PEG2000-thiol is a conjugate containing amino, PEG and thiol groups, used for drug delivery, material modification and chemical synthesis.
Cat. No.: HY-W998680
CAS No.: 2228857-33-6
Synonyms: 5-FITC-Maleimide
Synonyms: Maytansinoid DM3
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DM3 (Maytansinoid DM3), a Maytansine (HY-13674) analog bearing disulfide or thiol groups, and is a tubulin inhibitor. DM3 a cytotoxic moiety of antibody-drug conjugates (ADCs) .
Synonyms: NTCB
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2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives .
Cat. No.: HY-W441004
CAS No.: 144735-82-0
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DSPE-Thiol is a modified phospholipid containing a reactive thiol group (-SH), featuring two saturated stearoyl chains, and used mainly for liposome and nanoparticle bioconjugation. DSPE-Thiol helps attach targeting ligands, stabilize membranes, and form covalent bonds .
Cat. No.: HY-D1364
CAS No.: 1869968-64-8
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Research Areas:
Biotin-PEG7-Maleimide is a biotinylation reagent that reacts with thiol groups (SH). Biotin-PEG7-Maleimide can be used as Drug-Linker Conjugates for ADCs .
Cat. No.: HY-W190932
CAS No.: 2304558-24-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
