17 Results for "

thrombospondin 1

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "thrombospondin 1" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P701325
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: THBS1; THBS; thrombospondin 1; thrombospondin-1p180; TSP1; thrombospondin-1; TSP; Glycoprotein G; THBS-1; thrombospondin-P50; TSP-1; THBS1 Protein
Species:  
Mouse
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P70725
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: THBS1; THBS; thrombospondin 1; thrombospondin-1p180; TSP1; thrombospondin-1; TSP; Glycoprotein G; THBS-1; thrombospondin-P50; TSP-1; THBS1 Protein
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-13545
CAS No.: 251579-55-2
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

ABT-510 is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer. ABT-510 also reduces angiogenesis and inflammatory responses in a murine model of inflammatory bowel disease. ABT-510 can be used in studies of cancer (particularly epithelial ovarian cancer) and inflammatory bowel disease (IBD) .
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1
1 Cited Publications
Cat. No.: HY-13545B
CAS No.: 442526-87-6
Purity:  99.61%
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

ABT-510 acetate is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer. ABT-510 acetate also reduces angiogenesis and inflammatory responses in a murine model of inflammatory bowel disease. ABT-510 acetate can be used in studies of cancer (particularly epithelial ovarian cancer) and inflammatory bowel disease (IBD) .
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1
1 Cited Publications
Cat. No.: HY-P83750
Synonyms: TSP; THBS; TSP1; TSP-1; THBS-1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P0144
CAS No.: 149234-04-8
Target:  

CD47 Apoptosis

Research Areas:  

Inflammation/Immunology

Thrombospondin-1 (1016-1023) (human, bovine, mouse), is the C-terminal end of the native sequence of Thrombospondin-1 (TSP-1), is a CD47 agonist peptide .
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Cat. No.: HY-P3968
CAS No.: 149234-06-0
Target:  

CD47

Research Areas:  

Others

Thrombospondin-1 (1016-1021) (human, bovine, mouse), a Thrombospondin-1-derived peptide, is a truncated peptide devoid of CD47-binding activity .
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Cat. No.: HY-P11205A
Synonyms: Cys-txCD47 TFA
Cys-PKHB1 (Cys-txCD47) TFA is a peptide conjugated to PKHB1, a CD47 agonist peptide and a thrombospondin-1 peptide mimic with antitumor effects. PKHB1 induces mitochondrial alterations, ROS generation, intracellular Ca + accumulation, and calcium-dependent cell death in breast cancer cells. PKHB1 induces immune system activation in breast cancer cells through immunogenic cell death .
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Cat. No.: HY-P10371
CAS No.: 1505523-99-8
Synonyms: txCD47
PKHB1 (txCD47) is a CD47 agonist and Thrombospondin-1 peptide mimetic. PKHB1 activates CD47 and triggers Caspase-independent, calcium-dependent cell death via mitochondrial alterations, ROS production, endoplasmic reticulum morphological changes, and dissipation of mitochondrial membrane potential. PKHB1 induces the exposure of Calreticulin, HSP70, and HSP90, thereby driving immunogenic cell death. PKHB1 promotes intratumoral CD8 + T cell infiltration and inhibits breast tumorigenesis. PKHB1 reduces HSV-1 levels and alleviates the severity of herpes simplex keratitis. PKHB1 can be used in research related to breast cancer, herpes simplex keratitis, and T-cell acute lymphoblastic leukemia .
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Cat. No.: HY-P3996
CAS No.: 945373-85-3
Target:  

Peptides

Research Areas:  

Cancer

Properdistatin is a peptide derived from the thrombospondin 1 (TSP-1) domain of properdin. Properdistatin inhibits angiogenesis and improves vascular function. Properdistatin has the potential for the research of melanoma .
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Cat. No.: HY-P3972
CAS No.: 149234-05-9
Target:  

TGF-β Receptor

Research Areas:  

Cancer

H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide from C7 with a domain that supports cell attachment. H-ILE-ARG-VAL-VAL-MET-OH is also the sequence fragment that binds to the thrombospondin-1 (TS1) receptor .
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Cat. No.: HY-P86189
Synonyms: thrombospondin-1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P11205
CAS No.: 2378833-51-1
Synonyms: Cys-txCD47
Cys-PKHB1 (Cys-txCD47) is a peptide conjugated to PKHB1, a CD47 agonist peptide and a thrombospondin-1 peptide mimic with antitumor effects. PKHB1 induces mitochondrial alterations, ROS generation, intracellular Ca + accumulation, and calcium-dependent cell death in breast cancer cells. PKHB1 induces immune system activation in breast cancer cells through immunogenic cell death .
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Cat. No.: HY-P83530
Synonyms: TSP; THBS; TSP1; TSP-1; THBS-1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

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Cat. No.: HY-P83530A
Synonyms: TSP; THBS; TSP1; TSP-1; THBS-1

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

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Cat. No.: HY-165339
CAS No.: 54925-87-0
Target:  

TGF-β Receptor MMP

Research Areas:  

Others

Lysyl-phenylalanyl-lysine (Compound KFK) is a tripeptide and belongs to the peptide segments related to thrombospondin-1 (TSP-1) (HY-P0299). Lysyl-phenylalanyl-lysine can activate LAP-TGF-β1 and release active TGF-β1, thereby inhibiting abnormal expression of MMP. Lysyl-phenylalanyl-lysine can be used for research on skin aging-related diseases and poor wound healing .
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Cat. No.: HY-182611
CAS No.: 1637468-93-9
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology Cancer

SRI-31277 is a thrombospondin 1 (TSP-1) inhibitor with a human target pIC50 of 8.28 nM and in vivo activity, and exhibits a very short plasma half-life with intravenous administration.SRI-31277 inhibits interaction between TSP-1 and the latency-associated peptide (LAP) of latent TGF-β, blocking TSP-1-mediated TGF-β activation.SRI-31277 can be used for the research of multiple myeloma and fibrotic conditions .
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