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xanthine dehydrogenase

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By Targets:	Xanthine Oxidase (3) Biochemical Assay Reagents (1) Reference Standards (1)
By Research Areas:	Inflammation/Immunology (1) Metabolic Disease (4)
Oligonucleotides:	siRNA drugs (2) siRNAs (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W012658

2-Methylacetophenone O-Methylacetophenone	Xanthine Oxidase	Metabolic Disease Inflammation/Immunology
2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a **xanthine dehydrogenase (XDH*) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine* to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust .

HY-E70923

Xanthine dehydrogenase, Microorganism	Biochemical Assay Reagents	Metabolic Disease
Xanthine dehydrogenase, Microorganism (EC 1.17.1.4) belongs to the molybdenum-containing hydroxylase family and participates in the oxidative metabolism of purines. Xanthine dehydrogenase, Microorganism (EC 1.17.1.4) is a homodimer and can be converted into xanthine oxidase through reversible thiol oxidation or irreversible proteolytic modification.

HY-19164

BOF-4272	Xanthine Oxidase	Metabolic Disease
BOF-4272 is a xanthine oxidase/xanthine dehydrogenase inhibitor. BOF-4272 can be used for hyperuricemia research .

HY-W012658R

2-Methylacetophenone (Standard) O-Methylacetophenone (Standard)	Reference Standards Xanthine Oxidase	Metabolic Disease
2-Methylacetophenone (O-Methylacetophenone) (Standard) is the analytical standard of 2-Methylacetophenone (HY-W012658). This product is intended for research and analytical applications. 2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a **xanthine dehydrogenase (XDH*) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine* to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust .

2-Methylacetophenone O-Methylacetophenone	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Xanthine Oxidase
2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a **xanthine dehydrogenase (XDH*) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine* to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust .

2-Methylacetophenone (Standard) O-Methylacetophenone (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Xanthine Oxidase
2-Methylacetophenone (O-Methylacetophenone) (Standard) is the analytical standard of 2-Methylacetophenone (HY-W012658). This product is intended for research and analytical applications. 2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a **xanthine dehydrogenase (XDH*) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine* to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust .

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82212

	Xanthine Oxidase Antibody (YA1957) xanthine dehydrogenase; xanthine oxidase; xanthine oxidoreductase; XD; XDH; xdha; XO; xor	WB, IHC-P	Human, Mouse, Rat
	Xanthine Oxidase Antibody (YA1957) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Xanthine Oxidase.

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Zotresiran sodium		siRNAs siRNA drugs
Zotresiran sodium is a siRNA targeted to xanthine dehydrogenase.

Zotresiran		siRNAs siRNA drugs
Zotresiran is a siRNA targeted to xanthine dehydrogenase.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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