577-16-2
577-16-2
Chemical Structure
2-Methylacetophenone
Synonym(s): O-Methylacetophenone
- CAS No.: 577-16-2
- Formula:C9H10O
- Molecular Weight:134.18
IUPAC Name: 1-(o-tolyl)ethan-1-one
InChIKey: YXWWHNCQZBVZPV-UHFFFAOYSA-N
SMILES: CC(C1=CC=CC=C1C)=O
Biological Activity: 2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a xanthine dehydrogenase (XDH) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust[1][2].
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2-Methylacetophenone | 99.39% | 2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a xanthine dehydrogenase (XDH) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust. | ||||||||||||||||||||
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2-Methylacetophenone (Standard) | ≥98% | 2-Methylacetophenone (O-Methylacetophenone) (Standard) is the analytical standard of 2-Methylacetophenone (HY-W012658). This product is intended for research and analytical applications. 2-Methylacetophenone (O-Methylacetophenone), acetophenone derivative and acaricide, is a xanthine dehydrogenase (XDH) inhibitor. 2-Methylacetophenone competitively binds to the XDH active site, blocking the pathway for xanthine to be converted to uric acid. 2-Methylacetophenone can be used for the study of hyperuricemia and house dust. | ||||||||||||||||||||
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References
- [1]. Oh MS, Yang JY, Lee HS. Acaricidal toxicity of 2'-hydroxy-4'-methylacetophenone isolated from Angelicae koreana roots and structure-activity relationships of its derivatives. J Agric Food Chem. 2012 Apr 11;60(14):3606-11. [Content Brief]
- [2]. Chen M, et al. Potential candidates from a functional food Zanthoxyli Pericarpium (Sichuan pepper) for the management of hyperuricemia: high-through virtual screening, network pharmacology and dynamics simulations. Front Endocrinol (Lausanne). 2024 Dec 11;15:1436360. [Content Brief]
