142181-44-0
Chemical Structure
BOF-4272
- CAS No.: 142181-44-0
- Formula:C18H14N4O3S
- Molecular Weight:366.39
IUPAC Name: 8-(3-methoxy-4-(phenylsulfinyl)phenyl)pyrazolo[1,5-a][1,3,5]triazin-4(1H)-one
InChIKey: VEJLWJSERUNEJY-UHFFFAOYSA-N
SMILES: O=C1N=CNC2=C(C3=CC=C(S(C4=CC=CC=C4)=O)C(OC)=C3)C=NN21
Biological Activity: BOF-4272 is a xanthine oxidase/xanthine dehydrogenase inhibitor. BOF-4272 can be used for hyperuricemia research[1][2].
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BOF-4272 | BOF-4272 is a xanthine oxidase/xanthine dehydrogenase inhibitor. BOF-4272 can be used for hyperuricemia research. | |||||||||||||||||||||
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- [1]. NISHIMURA, et al. Local Disposition of a New Xanthine Oxidase/Xanthine Dehydrogenase Inhibitor, BOF-4272, in Rat Liver.. Biological & Pharmaceutical Bulletin, 1994. 17(9), 1301–1304.
- [2]. Naito S, et al. Enantioselective uptake of BOF-4272, a xanthine oxidase inhibitor with a chiral sulfoxide, by isolated rat hepatocytes. Yakugaku Zasshi. 2001 Dec;121(12):989-94. [Content Brief]
Keywords