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Cat. No.: HY-N21775

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Shashenoside I

Shashenoside I is a phenylpropanoid glycoside found in Dendrobium aurantiacum var. denneanum. Shashenoside I exhibits selective cytotoxicity against acute myeloid leukemia cells (IC₅₀ = 4.17 μM), while no activity is detected against other tumor cell lines. Shashenoside I can be used in research on acute myeloid leukemia.

For research use only. We do not sell to patients.

CAS No.: 138614-62-7
Formula: C₂₂H₃₂O₁₃
Molecular Weight:504.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Shashenoside I Chemical Structure

CAS No.: 138614-62-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
MV4-11	IC50	4.17 μM	Cytotoxicity against human acute myeloid leukemia MV4-11 cells incubated for 72 h assessed by MTT assay. Cytotoxicity against human acute myeloid leukemia MV4-11 cells incubated for 72 h assessed by MTT assay.	23702921

In Vitro

Shashenoside I (compound 4) (0.625-20 μM; 72 h) exhibits selective cytotoxicity against human acute myeloid leukemia MV4-11 cells with an IC₅₀ of 4.17 μM, while showing no activity against 10 other human tumor cell lines (H1975, H358, A549, HepG-2, SMMC7721, HCT116, MDA-MB-231, MCF-7, A2058, PANC-1) at 10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 138614-62-7
Molecular Weight 504.49
Formula C₂₂H₃₂O₁₃
SMILES

O(C1=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C(OC)=CC(CC=C)=C1)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Xiong L, et al. Phenolic glucosides from Dendrobium aurantiacum var. denneanum and their bioactivities. Molecules (Basel, Switzerland). 2013 May 23;18(6):6153-60.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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