2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Sulfinalol

Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity.

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Sulfinalol

Sulfinalol 화학구조

CAS No. : 66264-77-5

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Other Forms of Sulfinalol:

Sulfinalol Related Antibodies

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제품 설명

Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity[1].

IC50 & Target

β-adrenoceptor

 

In Vivo

Sulfinalol shows direct vasodilator activity and antihypertensive activity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mongrel dogs weighing 8.7-21.2 kg were anesthetized with pentobarbital (30-35 mg/kg, i.v., followed by a continuous infusion of 4 mg/kg/h)[1]
Dosage: 0-100 µg
Administration: Intraarterial injection
Result: Increased blood flow in the sympathetically denervated hindlimb of anesthetized dogs.
Animal Model: Male spontaneously hypertensive rats (SHR)[1]
Dosage: 2.5 mg/kg
Administration: Oral administration
Result: Reduced pressure of conscious spontaneously hypertensive rats.
분자량

377.50

화학식

C20H27NO4S
CAS No.
SMILES

COC(C=C1)=CC=C1CCC(C)NCC(C2=CC(S(C)=O)=C(O)C=C2)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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Sulfinalol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfinalol66264-77-5Adrenergic ReceptorBeta ReceptorVasodilator activityOrally activeInhibitorinhibitorinhibit

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상품명:
Sulfinalol
Cat. No.:
HY-106499
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