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  4. TCO-PNB ester

TCO-PNB ester is an amine-reactive building block used for modification of amine-containing molecule. TCO-PNB ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group.

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TCO-PNB ester

TCO-PNB ester 화학구조

CAS No. : 1438415-89-4

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

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Other Forms of TCO-PNB ester:

TCO-PNB ester Related Antibodies

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제품 설명

TCO-PNB ester is an amine-reactive building block used for modification of amine-containing molecule. TCO-PNB ester contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing a Tetrazine group[1].

분자량

291.30

화학식

C15H17NO5
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(OC1=CC=C([N+]([O-])=O)C=C1)O[C@H]2CC/C=C/CCC2
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 50 mg/mL (171.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4329 mL 17.1644 mL 34.3289 mL
5 mM 0.6866 mL 3.4329 mL 6.8658 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 98.52%

SDS (394 KB)

COA (247 KB) HNMR (239 KB) RP-HPLC (87 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.4329 mL 17.1644 mL 34.3289 mL 85.8222 mL
5 mM 0.6866 mL 3.4329 mL 6.8658 mL 17.1644 mL
10 mM 0.3433 mL 1.7164 mL 3.4329 mL 8.5822 mL
15 mM 0.2289 mL 1.1443 mL 2.2886 mL 5.7215 mL
20 mM 0.1716 mL 0.8582 mL 1.7164 mL 4.2911 mL
25 mM 0.1373 mL 0.6866 mL 1.3732 mL 3.4329 mL
30 mM 0.1144 mL 0.5721 mL 1.1443 mL 2.8607 mL
40 mM 0.0858 mL 0.4291 mL 0.8582 mL 2.1456 mL
50 mM 0.0687 mL 0.3433 mL 0.6866 mL 1.7164 mL
60 mM 0.0572 mL 0.2861 mL 0.5721 mL 1.4304 mL
80 mM 0.0429 mL 0.2146 mL 0.4291 mL 1.0728 mL
100 mM 0.0343 mL 0.1716 mL 0.3433 mL 0.8582 mL
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TCO-PNB ester Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TCO-PNB ester1438415-89-4Biochemical Assay Reagentsamine-reactive building blockInhibitorinhibitorinhibit

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상품명:
TCO-PNB ester
Cat. No.:
HY-141175
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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