1. Cell Cycle/DNA Damage Cytoskeleton
  2. Microtubule/Tubulin
  3. Tubulin inhibitor 27

Tubulin inhibitor 27 (DYT-1) is a tubulin polymerisation inhibitor with an IC50 of 25.6 µM. Tubulin inhibitor 27 shows anti-angiogenesis and antitumor activities.

For research use only. We do not sell to patients.

Tubulin inhibitor 27 Chemical Structure

Tubulin inhibitor 27 Chemical Structure

CAS No. : 184579-57-5

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Description

Tubulin inhibitor 27 (DYT-1) is a tubulin polymerisation inhibitor with an IC50 of 25.6 µM. Tubulin inhibitor 27 shows anti-angiogenesis and antitumor activities[1].

IC50 & Target

IC50: 25.6 µM (Tubulin polymerisation)[1]

In Vitro

Tubulin inhibitor 27 (DYT-1) shows anti-proliferation activity with IC50 values of 6.2 µM and 7.9 µM against K562 and Jurkat, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Tubulin inhibitor 27 (DYT-1) shows anti-angiogenesis activity in Zebrafish with an IC50 of 38.4 µM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

349.38

Formula

C21H19NO4

CAS No.
SMILES

O=C(C1=CC(OC)=C(OC)C(OC)=C1)/C=C/C2=CC=NC3=CC=CC=C23

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Tubulin inhibitor 27 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Tubulin inhibitor 27
Cat. No.:
HY-144817
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