1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. Microtubule/Tubulin
  3. Tubulin inhibitor 27

Tubulin inhibitor 27 

Cat. No.: HY-144817
Handling Instructions

Tubulin inhibitor 27 (DYT-1) is a tubulin polymerisation inhibitor with an IC50 of 25.6 µM. Tubulin inhibitor 27 shows anti-angiogenesis and antitumor activities.

For research use only. We do not sell to patients.

Tubulin inhibitor 27 Chemical Structure

Tubulin inhibitor 27 Chemical Structure

CAS No. : 184579-57-5

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Description

Tubulin inhibitor 27 (DYT-1) is a tubulin polymerisation inhibitor with an IC50 of 25.6 µM. Tubulin inhibitor 27 shows anti-angiogenesis and antitumor activities[1].

IC50 & Target

IC50: 25.6 µM (Tubulin polymerisation)[1]

In Vitro

Tubulin inhibitor 27 (DYT-1) shows anti-proliferation activity with IC50 values of 6.2 µM and 7.9 µM against K562 and Jurkat, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Tubulin inhibitor 27 (DYT-1) shows anti-angiogenesis activity in Zebrafish with an IC50 of 38.4 µM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

349.38

Formula

C21H19NO4

CAS No.
SMILES

O=C(C1=CC(OC)=C(OC)C(OC)=C1)/C=C/C2=CC=NC3=CC=CC=C23

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
Tubulin inhibitor 27
Cat. No.:
HY-144817
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