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Cat. No.: HY-147887

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Tubulin inhibitor 28

Tubulin inhibitor 28 (compound 2g) is a potent tubulin inhibitor with an IC₅₀ value of 1.2 µM. Tubulin inhibitor 28 shows anti-proliferative activity for MCF-7 cells.

For research use only. We do not sell to patients.

CAS No.: 71112-91-9
Formula: C₁₂H₈Br₂S₂
Molecular Weight:376.13

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Tubulin inhibitor 28 Chemical Structure

CAS No.: 71112-91-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Tubulin inhibitor 28 (compound 2g) is a potent tubulin inhibitor with an IC₅₀ value of 1.2 µM. Tubulin inhibitor 28 shows anti-proliferative activity for MCF-7 cells^[1].

IC₅₀ & Target

IC₅₀: 1.2 µM (tubulin)^[1].

In Vitro

Tubulin inhibitor 28 (compound 2g) shows anti-proliferative activity with an IC₅₀ value of >10 µM for MCF-7 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 71112-91-9
Molecular Weight 376.13
Formula C₁₂H₈Br₂S₂
SMILES

BrC1=CC=CC=C1SSC2=CC=CC=C2Br
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Khodyuk RGD, et al. Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity. Bioorg Chem. 2020 Aug;101:104017. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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