Tubulin polymerization-IN-31
Tubulin polymerization-IN-31 (Compound 4c) is a tubulin polymerization inhibitor with an IC50 of 3.64 μM. Tubulin polymerization-IN-31 induces cancer cell apoptosis and shows antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 2421121-79-9
- Formula: C18H13ClFN3
- Molecular Weight:325.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 3.64 μM (Tubulin polymerization)[1]
Tubulin polymerization-IN-31 (Compound 4c) shows antitumor activities with IC50 values of 6.02 ± 0.5, 8.45 ± 1.0 and 6.28 ± 0.6 μM against HepG2, HCT-116 and MCF-7, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2421121-79-9
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Molecular Weight 325.77
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Formula C18H13ClFN3
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SMILES
N#CC1=C2CCCCC2=C(C3=C(F)C=CC=C3Cl)C(C#N)=C1N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)