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Cat. No.: HY-156271

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Tubulin polymerization-IN-52

Tubulin polymerization-IN-52 (compound SC23) is a potent tubulin polymerization inhibitor, with an IC₅₀ of 2.9 μM.

For research use only. We do not sell to patients.

CAS No.: 2108615-05-8
Formula: C₂₁H₁₈F₃N₅O₃
Molecular Weight:445.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Tubulin polymerization-IN-52 Chemical Structure

CAS No.: 2108615-05-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Tubulin polymerization-IN-52 (compound SC23) is a potent tubulin polymerization inhibitor, with an IC₅₀ of 2.9 μM^[1].

Chemical Information

CAS No. 2108615-05-8
Molecular Weight 445.39
Formula C₂₁H₁₈F₃N₅O₃
SMILES

O=C(NC1=CC=CC=C1C(N2)=O)[C@@H]2CC(NCCN3C4=CC=CC=C4N=C3C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Horgan MJ, et al. Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro Approach. J Chem Inf Model. 2023 Sep 29. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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