Tubulin polymerization-IN-60
Tubulin polymerization-IN-60 (BF3) is a tubulin polymerization inhibitor with anticancer activity. Tubulin polymerization-IN-60 (BF3) belongs to the colchicine binding site inhibitors (CBSIs) and disturbs cell cycle progression leading to G2/M arrest and apoptosis.
For research use only. We do not sell to patients.
- CAS No.: 2361303-91-3
- Formula: C25H22O6
- Molecular Weight:418.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Tubulin polymerization-IN-60 (BF3) inhibits cell proliferation in a dose-dependent manner, with IC50 yielding 0.09 ± 0.01 μM, 0.11 ± 0.01 μM and 0.18 ± 0.05 μM for A375, MDA-MB435S and WM9, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2361303-91-3
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Molecular Weight 418.44
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Formula C25H22O6
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SMILES
O=C(C1=C(C2=CC=CC=C2)OC3=C1C=CC=C3OC)C4=CC(OC)=C(C(OC)=C4)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tubulin polymerization-IN-60 Related Classifications
HY-163356 Related Classifications
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