Tubulin polymerization-IN-64

Tubulin polymerization-IN-64 (Compound 8a) is an inhibitor for tubulin polymerization by occupying the colchicine binding site of tubulin, with IC50 of 6.9 μM. Tubulin polymerization-IN-64 inhibits proliferations of cancer cells A549, HeLa, HCT116 and HT-29, with IC50s of 2.42, 10.33, 6.28, 5.33 μM, respectively. Tubulin polymerization-IN-64 arrests cell cycle at G2/M phase, induces apoptosis in A549.

For research use only. We do not sell to patients.

  • Formula: C25H25NO6
  • Molecular Weight:435.47
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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