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Urease-IN-4 is an effective inhibitor of urease with an IC50 value of 1.64 µM. Urease-IN-4 has low cytotoxicity and shows inhibitory activity on P. vulgaris with an IC50 value of 15.27 µg/mL.

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Urease-IN-4

Urease-IN-4 Estructura química

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Descripciòn

Urease-IN-4 is an effective inhibitor of urease with an IC50 value of 1.64 µM. Urease-IN-4 has low cytotoxicity and shows inhibitory activity on P. vulgaris with an IC50 value of 15.27 µg/mL[1].

IC50 & Target

IC50: 1.64 µM (Urease)[1]

In Vitro

Urease-IN-4 (Compound 6e) (100 µM; 72 h) has insignificant effect on the viability of MOLT-4 cells, and the cell viability percent is 91.7 %[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: MOLT-4 cells.
Concentration: 100 µM.
Incubation Time: 72 h.
Result: Showed low cytotoxicity.
Peso molecular

320.41

Fòrmula

C16H20N2O3S

SMILES

CCCCNC(CC1SC(N(C1=O)CC2=CC=CC=C2)=O)=O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Referencias
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Urease-IN-4 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Urease-IN-4
Cat. No.:
HY-152668
Cantidad:
MCE Japan Authorized Agent: