Life Chemicals CNS Focused Screening Library
The incidence and significance of central nervous system diseases are increasing at an alarming rate all over the world. Although substantial research efforts have been applied to develop new CNS-active drugs, only a few CNS disorders are addressed satisfactorily, while the remaining ones pose significant clinical challenges. Blood-brain barrier (BBB) permeability is one of the most important limiting factors in the design and development of novel CNS-targeted pharmaceuticals for the treatment of neurological disorders.
Carefully selected from the HTS Compound Collection to meet the parameters optimized for high BBB-permeability, our CNS Focused Screening Library comprising over 30,300 structurally-diverse and potentially CNS-active screening compounds. This original Screening Compound Library is aimed at supporting CNS drug design projects and HTS efforts in search for novel neurotherapeutics.
- Excel
- SDF
- Manual
Product Details
• A unique collection of 30,300 highly CNS-like diverse molecules.
• Novel screening compounds synthesized in-house.
• Several formatting options available in 384- or 96-well microplates.
• Competitive pricing and convenient terms.
• Application of rigorous drug-likeness filters.
• Assured ≥ 90 % purity confirmed by LCMS and/or NMR data.
• Guaranteed hit re-supply, product scale-up.
• Databases and compounds are provided by Life Chemicals.