α-Amylase-IN-14
α-Amylase-IN-14, a derivative of Nicotinic (HY-B0143), is an α-amylase inhibitor and has good interactions with α-amylase protein (-5.55 kcal/mol). α-Amylase-IN-14 is a dual anti-inflammatory and anti-hyperglycemic agent. α-Amylase-IN-14 exhibits good results against DPPH and ABTS radicals. α-Amylase-IN-14 can be used for the study of diabetes.
For research use only. We do not sell to patients.
- CAS No.: 1099611-82-1
- Formula: C13H9NO4
- Molecular Weight:243.21
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
α-Amylase-IN-14 (Compound 2h) (20-100 μM, 30 min) exhibits a half-maximal inhibitory concentration IC50 value of 12.88 μM against DPPH[1].
α-Amylase-IN-14 (20-100 μM) exhibits a half-maximal inhibitory concentration IC50 value of 16.35 μM against ABTS[1].
α-Amylase-IN-14 (2-10 μg, 10 min) exhibits a half-maximal inhibitory concentration IC50 value of 1.516 μg against α-Amylase[1].
α-Amylase-IN-14 (20-100 μM, 15 min) shows anti-inflammatory with IC50 value of 21.69 μM in human blood sample[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1099611-82-1
-
Molecular Weight 243.21
-
Formula C13H9NO4
-
SMILES
O=C(C1=CC=CN=C1)OC2=CC=C3OCOC3=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)