1,3-Bis-aminooxy propane dihydrochloride

Cat. No.: HY-116924A: Data Sheet
SDS
Handling Instructions
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1,3-Bis-aminooxy propane dihydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

1,3-Bis-aminooxy propane dihydrochloride Chemical Structure

CAS No. : 104845-82-1

Size	Stock	Quantity
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Other Forms of 1,3-Bis-aminooxy propane dihydrochloride:

1,3-Bis-aminooxy propane Get quote

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Purity & Documentation
References
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Description

1,3-Bis-aminooxy propane dihydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

Molecular Weight

179.05

Formula

C₃H₁₂Cl₂N₂O₂

CAS No.

104845-82-1

Appearance

Solid

SMILES

NOCCCON.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (698.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.5850 mL	27.9252 mL	55.8503 mL
5 mM	1.1170 mL	5.5850 mL	11.1701 mL
10 mM	0.5585 mL	2.7925 mL	5.5850 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Data Sheet (266 KB) SDS (252 KB) Handling Instructions (2659 KB)

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.5850 mL	27.9252 mL	55.8503 mL	139.6258 mL
	5 mM	1.1170 mL	5.5850 mL	11.1701 mL	27.9252 mL
	10 mM	0.5585 mL	2.7925 mL	5.5850 mL	13.9626 mL
	15 mM	0.3723 mL	1.8617 mL	3.7234 mL	9.3084 mL
	20 mM	0.2793 mL	1.3963 mL	2.7925 mL	6.9813 mL
	25 mM	0.2234 mL	1.1170 mL	2.2340 mL	5.5850 mL
	30 mM	0.1862 mL	0.9308 mL	1.8617 mL	4.6542 mL
	40 mM	0.1396 mL	0.6981 mL	1.3963 mL	3.4906 mL
	50 mM	0.1117 mL	0.5585 mL	1.1170 mL	2.7925 mL
	60 mM	0.0931 mL	0.4654 mL	0.9308 mL	2.3271 mL
	80 mM	0.0698 mL	0.3491 mL	0.6981 mL	1.7453 mL
	100 mM	0.0559 mL	0.2793 mL	0.5585 mL	1.3963 mL