1-Boc-4-cyanopiperidine
Based on 1 Customer Validation
1-Boc-4-cyanopiperidine is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: ≥99.0%
- CAS No.: 91419-52-2
- Formula: C11H18N2O2
- Molecular Weight:210.28
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E146 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 91419-52-2
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Appearance Solid
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Molecular Weight 210.28
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Formula C11H18N2O2
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Color White to off-white
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SMILES
N#CC1CCN(C(=O)OC(C)(C)C)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 100 mg/mL (475.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (597 KB)
- English - EN (597 KB)
- Français - FR (597 KB)
- Deutsch - DE (597 KB)
- Norwegian - NO (597 KB)
- Español - ES (597 KB)
- Swedish - SV (597 KB)
- Italian - IT (597 KB)
- Korean - KR (597 KB)
- Portuguese - PT (597 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7556 mL | 23.7778 mL | 47.5556 mL | 118.8891 mL |
| 5 mM | 0.9511 mL | 4.7556 mL | 9.5111 mL | 23.7778 mL | |
| 10 mM | 0.4756 mL | 2.3778 mL | 4.7556 mL | 11.8889 mL | |
| 15 mM | 0.3170 mL | 1.5852 mL | 3.1704 mL | 7.9259 mL | |
| 20 mM | 0.2378 mL | 1.1889 mL | 2.3778 mL | 5.9445 mL | |
| 25 mM | 0.1902 mL | 0.9511 mL | 1.9022 mL | 4.7556 mL | |
| 30 mM | 0.1585 mL | 0.7926 mL | 1.5852 mL | 3.9630 mL | |
| 40 mM | 0.1189 mL | 0.5944 mL | 1.1889 mL | 2.9722 mL | |
| 50 mM | 0.0951 mL | 0.4756 mL | 0.9511 mL | 2.3778 mL | |
| 60 mM | 0.0793 mL | 0.3963 mL | 0.7926 mL | 1.9815 mL | |
| 80 mM | 0.0594 mL | 0.2972 mL | 0.5944 mL | 1.4861 mL | |
| 100 mM | 0.0476 mL | 0.2378 mL | 0.4756 mL | 1.1889 mL |
1-Boc-4-cyanopiperidine Related Classifications
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