(1R,2R)-2-PCCA hydrochloride (Standard)
(1R,2R)-2-PCCA (hydrochloride) (Standard) is the analytical standard of (1R,2R)-2-PCCA (hydrochloride) (HY-100013A1). This product is intended for research and analytical applications. (1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC50 of 3 nM in cell-free assay, and 603 nM in cell assay.
For research use only. We do not sell to patients.
- CAS No.: 1609563-71-4
- Formula: C30H39Cl2N3O
- Molecular Weight:528.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1609563-71-4
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Molecular Weight 528.56
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Formula C30H39Cl2N3O
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SMILES
CCCC1=CC=C(C2=CC=C(N(C[C@@H](N)[C@@H](C)CC)C([C@H]3[C@H](C4=CC=CC=N4)C3)=O)C=C2)C=C1.[H]Cl.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Bi, Yingzhi, et al. Modulators of G Protein-Coupled Receptor 88. US 20110251204 A1.
[2]. Jin C, et al. Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor. ACS Chem Neurosci. 2014 Jul 16;5(7):576-87. [Content Brief]
[3]. Jin C, et al. Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies. ACS Chem Neurosci. 2016 Oct 19;7(10):1418-1432. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)